RE: Paracetamol for chronically stiff dogs

mark packer — Tue, 10 Oct 2017 23:15:15 GMT

This is a useful resource - vet anaesthesia support group;

http://www.vasg.org/

Stuff on CRI's, dose charts etc

RE: Paracetamol for chronically stiff dogs

mark packer — Tue, 10 Oct 2017 23:01:54 GMT

I gather paracetomol works better in the brain...good In Practice review in Nov 15 (Rob Pettitt and Alex German) - can search online for it....safe enough, unlikely to cause harm.

Paracetamol/codeine

Paracetamol/codeine (Pardale V; Dechra) is licensed in dogs for use in the management of pain but only for five days and not in conjunction with NSAIDs. Its use in the management of osteoarthritis, within the license, is therefore limited. However, in the human field paracetamol is now routinely used in conjunction with NSAIDs as an alternating protocol and we use similar protocols in our practice, albeit off licence. The licensed dose for Pardale V is one tablet per 12.5 kg twice daily which equates to 33.33 mg/kg of paracetamol. Paracetamol alone is not licensed but the recommended dose rate is 10 mg/kg twice daily. If Pardale V is used in conjunction with NSAIDs we use it at a dose rate of 10 mg/kg which equates to one tablet per 40 kg twice daily. Paracetamol/codeine may be useful in cases where NSAID intolerance has been reported or in cases where patients are already on steroid therapy for another reason. The course can be extended for longer than five days but this is again an off licence indication. Paracetamol should never be used in cats due to potentially fatal toxicity.