https://www.vetsurgeon.org/f/clinical-questions/26194/steroids-and-diabetics Is it ever possible to stabilise a diabetic dog and use steroids, have a older dog with loads of issues and following seemingly endless tests and procedures seems to have lymphocytic plasmacytic enteritis, we have tried diet and atopica , which has helpeden-USTelligent Community 10https://www.vetsurgeon.org/thread/185054?ContentTypeID=1Mon, 25 Sep 2017 22:52:56 GMT146601cc-3922-4be7-9974-7e1d4e45a66b:c7e151f7-17e3-485b-aeea-9a25a579541bBusybee<p>I have a cat in a similar situation and after asking for advice from a referral medic, she suggested using Chlorambucil instead of steroids (which she most definitely would not use!). Would this work in a dog?&nbsp;</p><div style="clear:both;"></div>https://www.vetsurgeon.org/thread/185023?ContentTypeID=1Mon, 25 Sep 2017 18:41:50 GMT146601cc-3922-4be7-9974-7e1d4e45a66b:0aed9031-430f-41cb-a4c3-8b2d31ed8f12Glenn Hodgson<p>No too.&nbsp; But cushingoid Diabetics are usually less stable, not dead.</p> <p>Budesomide has a high percentage 1St pass metabolism.&nbsp; Kinda expensive though (possibly less expensive than a 2x dose insulin Though)</p><div style="clear:both;"></div>https://www.vetsurgeon.org/thread/185022?ContentTypeID=1Mon, 25 Sep 2017 18:36:42 GMT146601cc-3922-4be7-9974-7e1d4e45a66b:766a7592-0b48-4563-a785-b099da90cb8dSarah Keir<p>It is possible - the corticosteroids (I think this is what you mean!) will give a degree of insulin resistance so you are likely to need more insulin. But once stable keep the corticosteroid dose stable otherwise you won&#39;t know how to adjust the insulin. (if that makes sense?)</p><div style="clear:both;"></div>https://www.vetsurgeon.org/thread/185018?ContentTypeID=1Mon, 25 Sep 2017 18:32:30 GMT146601cc-3922-4be7-9974-7e1d4e45a66b:3f5d1327-18e4-4c92-819f-926f318c2f80Martin Atkinson<p>The answer is no. But in the end this an issue of quality of life and which is going to cause the dog bigger issues. I would suspect and unstable diabetic needing larger doses of insulin provided it is monitored &nbsp;regularly is a better bet in those stakes than awful gut rot.</p><div style="clear:both;"></div>