https://www.vetsurgeon.org/f/clinical-questions/25727/diarrhoea-in-a-cat Would you treat a cat with profuse diarrhoea/on and off vomiting that has C. perfringes A gene identified by PCR? This is the only thing we have been able to identify and so far nothing has made any difference to the diarrhoea, but cerenia has helpeden-USTelligent Community 10https://www.vetsurgeon.org/thread/178693?ContentTypeID=1Tue, 09 May 2017 18:22:27 GMT146601cc-3922-4be7-9974-7e1d4e45a66b:fc29286d-533d-4c50-b59d-be70bdf1fa96Andrew Kent<p>Hi Jessie,</p> <p>The short answer is probably not - the a toxin gene is present in all strains of C perfringens whether pathogenic or not and there is a high chance of finding this in normal cats.</p> <p>It&#39;s one of the reasons that faecal PCR panels are very difficult to interpret but you may find some help in the following consensus statement:</p> <p><a target='_blank' href="http://onlinelibrary.wiley.com/doi/10.1111/j.1939-1676.2011.00821.x/full">http://onlinelibrary.wiley.com/doi/10.1111/j.1939-1676.2011.00821.x/full</a></p> <p>Andy</p> <p></p><div style="clear:both;"></div>https://www.vetsurgeon.org/thread/178692?ContentTypeID=1Tue, 09 May 2017 18:07:46 GMT146601cc-3922-4be7-9974-7e1d4e45a66b:559d8ed0-f04a-4bb2-b92b-69707e697db6Martin Atkinson<p>We need a bit more information: age, diet, previous treatment, duration, other investigations/blood tests etc</p><div style="clear:both;"></div>