https://www.vetsurgeon.org/f/clinical-questions/25623/anyone-any-good-at-cytology Saw a colleague&#39;s case this week whilst they&#39;re on hols. 5yo Bulldog with an infected thickened alopecic area above one of it&#39;s eyes. It&#39;s had a couple of two week courses of cephalexin - client doesn&#39;t bring it back as instructed before these finishen-USTelligent Community 10https://www.vetsurgeon.org/thread/177528?ContentTypeID=1Tue, 11 Apr 2017 07:58:34 GMT146601cc-3922-4be7-9974-7e1d4e45a66b:d9c61ed8-49f3-4961-b28e-3d8e27f68e77Kathryn Burton<p>Coming in for biopsy on Thurs so shall report back!</p><div style="clear:both;"></div>https://www.vetsurgeon.org/thread/177471?ContentTypeID=1Sun, 09 Apr 2017 00:25:49 GMT146601cc-3922-4be7-9974-7e1d4e45a66b:86182975-84a5-4505-9b73-82de7bc1de2egrumpyoldman<p>biopsy could be a focal cutaneous epitheliotrophic lymphoma. Seen it a few times in bulldogs. &nbsp;</p><div style="clear:both;"></div>https://www.vetsurgeon.org/thread/177391?ContentTypeID=1Wed, 05 Apr 2017 21:48:43 GMT146601cc-3922-4be7-9974-7e1d4e45a66b:8e935e0d-cb18-47ea-86f9-b6b3de1532b6Stephen Courtney<p>I agree with Adrian. no evidence of neoplasia in that field.</p> <p>I also agree with the suggested cause, and it seems to me control will be more likely than cure. Also would suggest 4-6 weeks on antibiotics, 2 isn&#39;t enough for a chronic problem.&nbsp;</p><div style="clear:both;"></div>https://www.vetsurgeon.org/thread/177386?ContentTypeID=1Wed, 05 Apr 2017 21:06:19 GMT146601cc-3922-4be7-9974-7e1d4e45a66b:7317a0f4-0352-45a8-baa3-65fc216087a4Adrian Caunter<p>In the absence of a more knowledgeable poster I&#39;ll happily give my opinion and be just as happily corrected if wrong too! I would completely agree that this doesn&#39;t seem consistent with the appearance of a histiocytoma. Generally speaking they exfoliate very well and give you a large population of round cells with a high nuclear to cytoplasmic ratio and commonly a concurrent population of lymphocytes especially as they approach resolution.</p> <p>I also agree that the majority of cells are pmns with some other inflammatory cells thrown in as well. I wonder if what you are seeing here are multinucleated giant cells. They can be seen for a number of reasons including ironically histiocytic disease but usually are a feature of chronic inflammation and in my experience &nbsp;possibly secondary to some kind of fb reaction. Now from the history a fb seems unlikely but perhaps a hair follicle has been exposed etc and is acting as such. Either way a. I think this cytology points more towards an inflammatory/infectious cause and b. I&#39;m not really sure I&#39;ve helped you get much closer to an answer for your patient! Good luck and keep us updated</p><div style="clear:both;"></div>