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<?xml-stylesheet type="text/xsl" href="https://www.vetsurgeon.org/utility/feedstylesheets/rss.xsl" media="screen"?><rss version="2.0" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:slash="http://purl.org/rss/1.0/modules/slash/" xmlns:wfw="http://wellformedweb.org/CommentAPI/"><channel><title>Oral sedatives</title><link>https://www.vetsurgeon.org/f/clinical-questions/25574/oral-sedatives</link><description>Does anyone have a favourite oral sedative that they think is really reliable? I have a very aggressive dog coming in for pts that I would ideally like as asleep as possible before she comes in!
I find ACP, diazepam and sileo all variable in their effectiveness</description><dc:language>en-US</dc:language><generator>Telligent Community 10</generator><item><title>RE: Oral sedatives</title><link>https://www.vetsurgeon.org/thread/176757?ContentTypeID=1</link><pubDate>Mon, 27 Mar 2017 16:57:29 GMT</pubDate><guid isPermaLink="false">146601cc-3922-4be7-9974-7e1d4e45a66b:75da9598-0392-4b5d-98ae-d3da5fdf7da0</guid><dc:creator>Daniella Sellick</dc:creator><description>&lt;p&gt;I have used oral medetomidine on these occasions in the past. 0.4ml/10kg. Has to be given onto the gums 40 minutes before due in. DO stress onto gums (like sileo), I&amp;#39;ve had one owner mix it in with food and obviouslyit had very little effect.&lt;/p&gt;&lt;div style="clear:both;"&gt;&lt;/div&gt;</description></item><item><title>RE: Oral sedatives</title><link>https://www.vetsurgeon.org/thread/176625?ContentTypeID=1</link><pubDate>Sat, 25 Mar 2017 12:07:03 GMT</pubDate><guid isPermaLink="false">146601cc-3922-4be7-9974-7e1d4e45a66b:60cff78f-727c-480c-bebf-4f2b82fef561</guid><dc:creator>Stephen Courtney</dc:creator><description>&lt;p&gt;[quote user=&amp;quot;Neil Wheadon&amp;quot;]&lt;/p&gt;
&lt;p&gt;[quote user=&amp;quot;Linda Filshie&amp;quot;]How about a hefty dose of phenobarb?[/quote]&lt;/p&gt;
&lt;p&gt;Has anyone actually tried this?&lt;/p&gt;
&lt;p&gt;The reason I ask is because I&amp;#39;ve seen ACP +/- diazepam fail on many occasions and would be interested to try this.&lt;/p&gt;
&lt;p&gt;What dose?&lt;/p&gt;
&lt;p&gt;&amp;nbsp; &amp;nbsp;Neil&lt;/p&gt;
&lt;div style="clear:both;"&gt;&lt;/div&gt;
&lt;p&gt;[/quote]&lt;/p&gt;
&lt;p&gt;&lt;/p&gt;
&lt;p&gt;Yes I have - twice. Large very aggressive GSD dogs that had to be PTS because they were so dangerous. they had come via the Police, and were being housed at a kennels we used to look after.&lt;/p&gt;
&lt;p&gt;I seem to recall giving about 30 x ACP 25mg and 30 x Epiphen 60mg. The kennel owner put the tablets in the animals&amp;#39; breakfast and i got there 2 hours later. Perhaps over-kill but in each case the dog was totally comatose and unresponsive, did not need the massive dose of domitor i had in mind. I still muzzled and got someone to hold the dog for me in case it woke up, and finished the job with intracardiac euthanasia solution. not pleasant but I don&amp;#39;t wrestle with aggressive dogs, end of.&amp;nbsp;&lt;/p&gt;
&lt;p&gt;&lt;/p&gt;&lt;div style="clear:both;"&gt;&lt;/div&gt;</description></item><item><title>RE: Oral sedatives</title><link>https://www.vetsurgeon.org/thread/176605?ContentTypeID=1</link><pubDate>Fri, 24 Mar 2017 23:52:59 GMT</pubDate><guid isPermaLink="false">146601cc-3922-4be7-9974-7e1d4e45a66b:442593f9-7de2-4914-921b-5ae575470523</guid><dc:creator>Utlendigur</dc:creator><description>&lt;p&gt;Is it still possible to get butorphanol in tablet form (Torbutrol)? I used this in combination with Acp a couple of times years ago for aggressive dog PTSs, and it did give much better sedation than Acp alone, but then the tablets became ridiculously expensive to keep in stock.&amp;nbsp;&lt;/p&gt;&lt;div style="clear:both;"&gt;&lt;/div&gt;</description></item><item><title>RE: Oral sedatives</title><link>https://www.vetsurgeon.org/thread/176602?ContentTypeID=1</link><pubDate>Fri, 24 Mar 2017 23:26:35 GMT</pubDate><guid isPermaLink="false">146601cc-3922-4be7-9974-7e1d4e45a66b:a0c56345-3cb2-48a3-b925-1c86dc60016c</guid><dc:creator>Neil Wheadon</dc:creator><description>&lt;p&gt;[quote user=&amp;quot;Michael Woodhouse&amp;quot;]&lt;/p&gt;
&lt;p&gt;When given to a calm dog on an empty stomach half an hour before visiting the vets? I dose at top end of dose range (3mg/kg or 1x10mg tablet per 3.3kg).&lt;/p&gt;
&lt;p&gt;There is an oral alpha 2 but I&amp;#39;ve not tried it or needed it with the little yellow pills.&lt;/p&gt;
&lt;p&gt;[/quote]&lt;/p&gt;
&lt;p&gt;Yes it will sedate them, but in these cases it simply needs to be enough to allow them to be safe to be handled. The ones I see consistently have been fed maybe up to 100mg of ACP and as soon as you try to do anything they will have you. This is why I have no faith in ACP at all. The last one I dealt with was a few months ago. Another vet had fed a 35kg mastiff dog 100mg. I ended up using a dog catcher and adding medetomidine as although the eyelids looked droopey it would still have you.&lt;/p&gt;
&lt;p&gt;This is the reason I asked about phenobarbitone and the dose required as I haven&amp;#39;t seen that done.&lt;/p&gt;
&lt;p&gt;&amp;nbsp; &amp;nbsp;Neil&lt;/p&gt;&lt;div style="clear:both;"&gt;&lt;/div&gt;</description></item><item><title>RE: Oral sedatives</title><link>https://www.vetsurgeon.org/thread/176599?ContentTypeID=1</link><pubDate>Fri, 24 Mar 2017 22:54:14 GMT</pubDate><guid isPermaLink="false">146601cc-3922-4be7-9974-7e1d4e45a66b:70b4d77f-6070-45cc-9822-3989a46bc4c1</guid><dc:creator>Michael Woodhouse</dc:creator><description>&lt;p&gt;[quote user=&amp;quot;Neil Wheadon&amp;quot;]The reason I ask is because I&amp;#39;ve seen ACP +/- diazepam fail on many occasions [/quote]&lt;/p&gt;
&lt;p&gt;When given to a calm dog on an empty stomach half an hour before visiting the vets? I dose at top end of dose range (3mg/kg or 1x10mg tablet per 3.3kg).&lt;/p&gt;
&lt;p&gt;There is an oral alpha 2 but I&amp;#39;ve not tried it or needed it with the little yellow pills.&lt;/p&gt;&lt;div style="clear:both;"&gt;&lt;/div&gt;</description></item><item><title>RE: Oral sedatives</title><link>https://www.vetsurgeon.org/thread/176596?ContentTypeID=1</link><pubDate>Fri, 24 Mar 2017 22:36:07 GMT</pubDate><guid isPermaLink="false">146601cc-3922-4be7-9974-7e1d4e45a66b:c6e8690d-8c08-4af7-bc87-3b6b73ac39aa</guid><dc:creator>Nicola Cole</dc:creator><description>&lt;p&gt;Great, thanks, have gone back and looked at the old thread as well. Thanks for all replies and ideas.&lt;/p&gt;&lt;div style="clear:both;"&gt;&lt;/div&gt;</description></item><item><title>RE: Oral sedatives</title><link>https://www.vetsurgeon.org/thread/176595?ContentTypeID=1</link><pubDate>Fri, 24 Mar 2017 22:14:06 GMT</pubDate><guid isPermaLink="false">146601cc-3922-4be7-9974-7e1d4e45a66b:2a7fe894-b917-44dc-84b9-75fb465f146e</guid><dc:creator>Rob Loxley</dc:creator><description>&lt;p&gt;[quote user=&amp;quot;Nicola M&amp;quot;]Does anyone have a favourite oral sedative that they think is really reliable?[/quote]&lt;/p&gt;
&lt;p&gt;If you do a search this has come up before a number of times.&lt;br /&gt;I quite like pentobarbital mixed in food, or domitor into the mouth&lt;/p&gt;&lt;div style="clear:both;"&gt;&lt;/div&gt;</description></item><item><title>RE: Oral sedatives</title><link>https://www.vetsurgeon.org/thread/176586?ContentTypeID=1</link><pubDate>Fri, 24 Mar 2017 20:01:48 GMT</pubDate><guid isPermaLink="false">146601cc-3922-4be7-9974-7e1d4e45a66b:48f92f37-7dbd-4971-a136-6c3cd628d1cd</guid><dc:creator>Nicola Cole</dc:creator><description>&lt;p&gt;[quote user=&amp;quot;Claire Fisher&amp;quot;]&lt;/p&gt;
&lt;p&gt;The aggressive dogs we PTS get phenobarb, diazepam and ACP. Works well for most of them.&lt;/p&gt;
&lt;div style="clear:both;"&gt;&lt;/div&gt;
&lt;p&gt;[/quote]&lt;/p&gt;
&lt;p&gt;is that at a full dose of each drug?&lt;/p&gt;&lt;div style="clear:both;"&gt;&lt;/div&gt;</description></item><item><title>RE: Oral sedatives</title><link>https://www.vetsurgeon.org/thread/176584?ContentTypeID=1</link><pubDate>Fri, 24 Mar 2017 19:37:10 GMT</pubDate><guid isPermaLink="false">146601cc-3922-4be7-9974-7e1d4e45a66b:bafa0dc3-af6c-4be4-a893-0f70f9221066</guid><dc:creator>Claire Fisher</dc:creator><description>&lt;p&gt;The aggressive dogs we PTS get phenobarb, diazepam and ACP. Works well for most of them.&lt;/p&gt;&lt;div style="clear:both;"&gt;&lt;/div&gt;</description></item><item><title>RE: Oral sedatives</title><link>https://www.vetsurgeon.org/thread/176574?ContentTypeID=1</link><pubDate>Fri, 24 Mar 2017 17:33:01 GMT</pubDate><guid isPermaLink="false">146601cc-3922-4be7-9974-7e1d4e45a66b:cf4e45a1-5d3c-4881-a6d9-ba8c3b9a3299</guid><dc:creator>Nicola Cole</dc:creator><description>&lt;p&gt;Yep I usually would just jab domitor after owner puts a muzzle on at home...but she&amp;#39;s so petrified just seeing if I can send her on her way without her getting so stressed.&lt;/p&gt;
&lt;p&gt;(I know I&amp;#39;m being soppy but I&amp;#39;ve known her for a while and although she&amp;#39;d happily eat me, once you&amp;#39;ve spent a good half hour with her bonding over treats she starts to trust you and gets a bit soppy and you see her softer side (it was a quiet morning last time I saw her so could take my time with her!)...that is until you try to do anything to her...then the process starts all over again!)&lt;/p&gt;&lt;div style="clear:both;"&gt;&lt;/div&gt;</description></item><item><title>RE: Oral sedatives</title><link>https://www.vetsurgeon.org/thread/176572?ContentTypeID=1</link><pubDate>Fri, 24 Mar 2017 17:11:22 GMT</pubDate><guid isPermaLink="false">146601cc-3922-4be7-9974-7e1d4e45a66b:91ea7ea2-5354-45f5-b9f3-4b0118f8b51e</guid><dc:creator>Clive Ansell</dc:creator><description>&lt;p&gt;[quote user=&amp;quot;Neil Wheadon&amp;quot;]&lt;/p&gt;
&lt;p&gt;[quote user=&amp;quot;Linda Filshie&amp;quot;]How about a hefty dose of phenobarb?[/quote]&lt;/p&gt;
&lt;p&gt;Has anyone actually tried this?&lt;/p&gt;
&lt;p&gt;The reason I ask is because I&amp;#39;ve seen ACP +/- diazepam fail on many occasions and would be interested to try this.&lt;/p&gt;
&lt;p&gt;What dose?&lt;/p&gt;
&lt;p&gt;[/quote]&lt;/p&gt;
&lt;p&gt;Yes, but not that reliable, but sometimes helps, and sometimes the only first option, even if it allows the owners to get it muzzled to allow injection i/m.&lt;/p&gt;
&lt;p&gt;Dose - as much as possible if just trying to flatten to pts.&lt;/p&gt;
&lt;p&gt;Usually though, I&amp;#39;ll try and inject one way or another after the owner has placed a muzzle - if the owners can&amp;#39;t/won&amp;#39;t do that, then I would follow Martins advice - go elsewhere. &amp;nbsp;&lt;/p&gt;&lt;div style="clear:both;"&gt;&lt;/div&gt;</description></item><item><title>RE: Oral sedatives</title><link>https://www.vetsurgeon.org/thread/176570?ContentTypeID=1</link><pubDate>Fri, 24 Mar 2017 16:57:07 GMT</pubDate><guid isPermaLink="false">146601cc-3922-4be7-9974-7e1d4e45a66b:763f47e9-d38a-416c-9745-e2ffd7e49af3</guid><dc:creator>Neil Wheadon</dc:creator><description>&lt;p&gt;[quote user=&amp;quot;Linda Filshie&amp;quot;]How about a hefty dose of phenobarb?[/quote]&lt;/p&gt;
&lt;p&gt;Has anyone actually tried this?&lt;/p&gt;
&lt;p&gt;The reason I ask is because I&amp;#39;ve seen ACP +/- diazepam fail on many occasions and would be interested to try this.&lt;/p&gt;
&lt;p&gt;What dose?&lt;/p&gt;
&lt;p&gt;&amp;nbsp; &amp;nbsp;Neil&lt;/p&gt;&lt;div style="clear:both;"&gt;&lt;/div&gt;</description></item><item><title>RE: Oral sedatives</title><link>https://www.vetsurgeon.org/thread/176564?ContentTypeID=1</link><pubDate>Fri, 24 Mar 2017 16:17:56 GMT</pubDate><guid isPermaLink="false">146601cc-3922-4be7-9974-7e1d4e45a66b:30df06f3-0e37-42ac-99a6-0f4ea254d2c1</guid><dc:creator>Clive Ansell</dc:creator><description>&lt;p&gt;I always find combination therapy works best, so may be a mixture of oral acp/diazepam/phenobarb,&amp;nbsp; enough to get a muzzle on at least. Then maybe inject acp/domitor/ketamine combination.&lt;/p&gt;
&lt;p&gt;If no good, get the police to shoot it.&lt;/p&gt;&lt;div style="clear:both;"&gt;&lt;/div&gt;</description></item><item><title>RE: Oral sedatives</title><link>https://www.vetsurgeon.org/thread/176561?ContentTypeID=1</link><pubDate>Fri, 24 Mar 2017 15:56:37 GMT</pubDate><guid isPermaLink="false">146601cc-3922-4be7-9974-7e1d4e45a66b:b21a4ec7-b1c9-4856-a0fe-c5c5008abb90</guid><dc:creator>Martin Atkinson</dc:creator><description>&lt;p&gt;Tell the owner to muzzle it and give it a shot of medetomidine when it comes in. If they can&amp;#39;t even do that suggest they may like to take their custom elsewhere.&lt;/p&gt;&lt;div style="clear:both;"&gt;&lt;/div&gt;</description></item><item><title>RE: Oral sedatives</title><link>https://www.vetsurgeon.org/thread/176559?ContentTypeID=1</link><pubDate>Fri, 24 Mar 2017 15:46:31 GMT</pubDate><guid isPermaLink="false">146601cc-3922-4be7-9974-7e1d4e45a66b:597c7eb5-1e60-4eb7-88e6-8c05e149dc50</guid><dc:creator>Linda Filshie</dc:creator><description>&lt;p&gt;How about a hefty dose of phenobarb?&lt;/p&gt;
&lt;p&gt;&lt;/p&gt;&lt;div style="clear:both;"&gt;&lt;/div&gt;</description></item></channel></rss>