https://www.vetsurgeon.org/f/clinical-questions/25452/obesity-pupd-cushing-tests Hi, would appreciate your thoughts on this case. 10 year old fn cross breed dog from my former assistant. Complaint: obesity and pupd. Sp graf urine: 1.008 Was suspecting Cushing, but results say otherwise: ACTH stim - cortisol pre: 138.6 + en-USTelligent Community 10https://www.vetsurgeon.org/thread/175058?ContentTypeID=1Fri, 24 Feb 2017 17:58:50 GMT146601cc-3922-4be7-9974-7e1d4e45a66b:4f876cf6-ea8c-4b52-b0c9-4ddf0a1d3c6bEilidh Corr<p>Matt said what I was going to.&nbsp;</p> <p>However if that pulls a blank I would revisit Cushing&#39;s. The basal levels are high. In the past I&#39;ve had to go to 17 hydroxyprogesterone to tie down difficult Cushing&#39;s cases. If they walk like a duck ...</p><div style="clear:both;"></div>https://www.vetsurgeon.org/thread/175056?ContentTypeID=1Fri, 24 Feb 2017 17:08:59 GMT146601cc-3922-4be7-9974-7e1d4e45a66b:e1af6caf-b1c2-4035-8c7e-e14c10a4ab2fMatt Hilary<p>Assuming sufficiently stable quantifying water intake and full urinalysis (dipstick, sediment exam, UPCR + culture) would be next step for me, followed by abdominal ultrasound (esp focussing on kidneys). Also calcium levels - not sure if you&#39;ve measured already.</p> <p>Agree not HAC or hypoT.</p><div style="clear:both;"></div>