https://www.vetsurgeon.org/f/clinical-questions/25231/lomustine Hi everyone, I hope Christmas was amazing and joyfull I have a question related to lomustine. I have to give Lomustine to a dog the is on a rescue treatment for t-cell lymphoma and at biochem check liver was fine, only have slight raised creatinineen-USTelligent Community 10https://www.vetsurgeon.org/thread/171176?ContentTypeID=1Tue, 27 Dec 2016 16:39:38 GMT146601cc-3922-4be7-9974-7e1d4e45a66b:b391d8fc-67c6-492e-b10f-8c3a7964fdd0Martin Atkinson<p>AFAIA lomustine isn&#39;t nephrotoxic so should be OK. I&#39;ve been treating a dog with soft tissue sarcoma and it was a bit of a juggling act as his liver enzymes were all raised so it required careful monitoring. As ever there has to be a risk/benefit assessment. However I wouldn&#39;t exceed 70mg/msq every 4 weeks especially if the liver is a bit iffy.</p><div style="clear:both;"></div>https://www.vetsurgeon.org/thread/171155?ContentTypeID=1Sun, 25 Dec 2016 23:17:43 GMT146601cc-3922-4be7-9974-7e1d4e45a66b:b99c0096-0419-4fe1-ad4e-01135fb58635Beats<p>in case no-one wiser posts:</p> <p>as far as i know yes - adminitser as planned.</p><div style="clear:both;"></div>