Does ACP decrease fear in dogs?

RE: Does ACP decrease fear in dogs?

Christina Smith — Sun, 16 Oct 2016 18:53:27 GMT

Mine died but that was before we knew about this MDR1 gene that some collies have. May have been the problem in this single incident. We can now test for those individuals and avoid a whole gamut of potentially serious drug induced events. See previous thread on MDR1

RE: Does ACP decrease fear in dogs?

Anthony Todd — Sun, 16 Oct 2016 17:46:22 GMT

PS i gave [I hope] 14 x 25mg ACP to a lethal alsatian at a guard dog facility and it still was lethal!

Is it possible to overdose ACP?? Someone must have done a LD50......

RE: Does ACP decrease fear in dogs?

Anthony Todd — Sun, 16 Oct 2016 12:59:02 GMT

[quote user="Christina Smith"] The dog was to be groomed [hence the acp], it was overdosed. No previous history of seizures.[/quote]

I've given 75 mg ACP, and more to collie sized dogs without problems, or even bite-saving effects.

Sounds like Trip Advisor "instant" "food poisoning" to me....

RE: Does ACP decrease fear in dogs?

Christina Smith — Sun, 16 Oct 2016 12:20:44 GMT

[quote user="Neil Wheadon"]

quote user="Christina Smith"] His seizure threshold was irreversibly lowered[/quote]

Can you explain this??

Sounds like my dog got died because it was vaccinated, co-incidence, something I tackle monthly (well explaining apparent links)

Neil

You are right - one single , bad experience. The dog was to be groomed [hence the acp], it was overdosed. No previous history of seizures.

RE: Does ACP decrease fear in dogs?

Neil Wheadon — Sat, 15 Oct 2016 13:38:14 GMT

[quote user="Christina Smith"] His seizure threshold was irreversibly lowered[/quote]

Can you explain this??

Sounds like my dog got died because it was vaccinated, co-incidence, something I tackle monthly (well explaining apparent links)

Neil

RE: Does ACP decrease fear in dogs?

Christina Smith — Sat, 15 Oct 2016 01:01:22 GMT

I had a very bad experience with ACP, a very nervous agorophobic rough collie given high dose ACP tablets poss as much as 75mg. His seizure threshold was irreversibly lowered and he never recovered. n=1

RE: Does ACP decrease fear in dogs?

Virginia Campbell — Fri, 14 Oct 2016 23:55:50 GMT

The longer I'm in practice the more I appreciate the wide variety of responses of individual animals to various types of drugs, especially analgesics and happy pills. The trouble with Hallowe'en (or bonfire night for the mainlanders) is that we only get one chance to guess the correct drug at the correct dose, by a route with variable absorption in each individual, and our guess will be tested under extreme conditions if the dog is very stressy.