https://www.vetsurgeon.org/f/clinical-questions/24933/rate-of-administration-of-colloids HI everyone, I keep finding the range 10-20 ml/kg as the recommended volume of colloid administration in 24 hours. Could anyone give me any practical examples of how quickly you would infuse this? For example , calculate a figure e.g. 15 ml/kg anden-USTelligent Community 10https://www.vetsurgeon.org/thread/166569?ContentTypeID=1Wed, 12 Oct 2016 00:11:14 GMT146601cc-3922-4be7-9974-7e1d4e45a66b:056bf4ec-0a7e-4742-8841-04c77ecabc62Michael Woodhouse<p>We stopped using colloids when they were all recalled as they were killing people. The only colloid we use is blood. We&#39;ve not missed them.</p> <p>The difference between crystaloids and colloids is their rate of redistribution to the interstitial space - in simplistic terms they hang around 4X as long therefore 1/4 what you&#39;d do with crystalloids.</p> <p style="margin-left:30px;">As colloids are not associated with an improvement in survival and are considerably more expensive than crystalloids, it is hard to see how their continued use in clinical practice can be justified. <a target='_blank' href="https://www.ncbi.nlm.nih.gov/pubmed/23450531"></a><a>https://www.ncbi.nlm.nih.gov/pubmed/23450531</a> </p> <p>We may well use crystalloids in an animal receiving blood, but it must be through a separate IV cannulae if using calcium containing fluid (we use mainly Hartmanns).</p><div style="clear:both;"></div>