https://www.vetsurgeon.org/f/clinical-questions/24512/dog-with-pu-pd I am dealing with a strange case. Been trying to figure it out for 2 years. Male,neutered Nova Scotia duck Tolling retriever, 6,5 years old. It was seen in april 2014, as the owner felt it had been lethargic for a few months. Loosing fur, and makingen-USTelligent Community 10https://www.vetsurgeon.org/thread/161387?ContentTypeID=1Fri, 01 Jul 2016 17:30:57 GMT146601cc-3922-4be7-9974-7e1d4e45a66b:4df42248-3396-4e3f-9cb7-ca4cf707e474Anthony Dennison<p>At an Endocrinology CPS at Liverpool Uni yesterday, they said Nova Scotia dogs have a 10 x higher incidence of Addison&#39;s than any other breed.</p> <p>Check your ACTH stim, but also ask the lab to run an aldosterone assay (usually there&#39;s enough left over from your ACTH stim so you don&#39;t need a 2nd sample). Some atypical addisonians are just cortisol deficient, or have increased sensitivity to aldosterone so it hasn&#39;t cause electrolyte abnormalities yet.</p> <p>If it does have a low ACTH stim, don&#39;t start Zycortal unless electrolytes become abnormal.</p><div style="clear:both;"></div>