PUPD cat

Re: PUPD cat

Alex Avery — Thu, 14 May 2009 09:23:41 GMT

I would agree that a UPC may be beneficial. Diabetes mellitus can also come on very quickly in cats and so the fructosamine may not have had enough time to become elevated and may be worth repeating (especially if a urine sample is collected by the owner at home and brought straight into the practice confirms continued presence of urine glucose).

Re: PUPD cat

Laurence Webb — Wed, 13 May 2009 23:58:26 GMT

Has it got/did it have an active urine sediment? If not then run a UPC on it. Also culture the urine. I'd wonder about a UTI superimposed on a CRF especially if it is antibiotic responsive. In dilute urine UTIs are much more likley to happen.

Bear in mind that if it's got an underrlying CRF then the normal lab ranges no longer apply to its creatinine levels - look at http://www.iris-kidney.com for guidelines, but even a creatinine <140umo/l can be seen in cats with CRF.

Do the kidneys feel normal? Imaging then to assess size and (if you've got ultrasound) internal architecture is a good idea. You could consider an IVU but if it's got renal failure then that may deteriorate renal function further. Ultimately biopsy is the best was to find out what's going on in the kidneys, but that can have an even worse effect on renal function!

Re: PUPD cat

beldather — Mon, 11 May 2009 20:21:21 GMT

Possibility of underlying renal insufficiency that has then got a cystitis or pyelonephritis? Any indications of casts etc in urine? Got any wizbang ultrasonagraphers in your practice?
Might be inclined to go for creatinine:cortisol ratio as if negative should rule out cushings, may be bit easier unless its a lovely cat.
Hope you get it sorted.

Regards

Blair

Re: PUPD cat

Tim Newton — Mon, 11 May 2009 16:00:31 GMT

Never seen DI in a cat, but possible if the SG is low enough. Pfizer have told me to allow at least 8 weeks withdrawal on Convenia for what it’s worth

Good luck

Tim