https://www.vetsurgeon.org/f/clinical-questions/24154/guineapig-with-submandibular-mass-and-respiratory-distress Adult male entire guineapig, kept next to another pig, both live inside and go outside regularly. Off colour 1 - 2 weeks, eating less, lost weight, owners suddenly noticed large submandibular mass. Exam - keeled over during brief exam with severe respiratoryen-USTelligent Community 10https://www.vetsurgeon.org/thread/156689?ContentTypeID=1Fri, 15 Apr 2016 12:05:39 GMT146601cc-3922-4be7-9974-7e1d4e45a66b:1b8401a2-3037-4ec0-b2a1-aab7017357e5Marie Kubiak<p>Hi,</p> <p>With the fluid aspiration and respiratory compromise&nbsp;there may be congestive heart failure - often associated with diffuse submandibular and ventral oedema and not at all&nbsp;unusual in elderly guinea pigs.&nbsp;</p> <p>Streptococcal infections are often associated with lymph node abscessation in GPs. A large submandibular mass would most commonly be abscessation (external trauma, dental disease, lymph node abscess but although a rare finding at this site primary neoplasia and mets to lungs can&#39;t be ruled out.</p> <p>Pneumonia is a common secondary consequence of debiliatation/dysphagia or primary pulmonary disease such as adenovirus or neoplasia.</p> <p>All speculation though without any diagnostics. Could be all of the above or something else entirely!</p> <p>Marie</p><div style="clear:both;"></div>