Cat with multicentric b cell lymphomahttps://www.vetsurgeon.org/f/clinical-questions/23611/cat-with-multicentric-b-cell-lymphoma Hi all, I&#39;ve had a cat sent to me from another vet practice to start chemotherapy for multicentric B cell lymphoma. He is 15yrs, MN and is also under treatment for septic arthritis in his left fore (diagnosed by consistent radiographs and high neutrophilen-USTelligent Community 10RE: Cat with multicentric b cell lymphomahttps://www.vetsurgeon.org/thread/148460?ContentTypeID=1Mon, 07 Dec 2015 09:45:43 GMT146601cc-3922-4be7-9974-7e1d4e45a66b:70147b2e-0059-4259-bec2-c72b4813b377Kate Richardson<p>Thankyou Gerry</p><div style="clear:both;"></div>RE: Cat with multicentric b cell lymphomahttps://www.vetsurgeon.org/thread/148457?ContentTypeID=1Mon, 07 Dec 2015 09:38:59 GMT146601cc-3922-4be7-9974-7e1d4e45a66b:742afe14-c1e9-476f-b4c2-e347b52ea73eGerry Polton<p>Reasons against: indolent disease usually non-responsive to chemo, age, concurrent morbidity</p> <p>B/T typing is not of prognostic value in cats though grade of disease is: low grade (indolent) versus high grade (normal).</p><div style="clear:both;"></div>RE: Cat with multicentric b cell lymphomahttps://www.vetsurgeon.org/thread/148455?ContentTypeID=1Mon, 07 Dec 2015 09:32:35 GMT146601cc-3922-4be7-9974-7e1d4e45a66b:0a343a74-e820-4bc6-b548-20d5041c7fa9Kate Richardson<p></p> <p>I have to say I read this late last night and my initial thoughts were I would give serious consideration as to whether to treat or not, but didn&#39;t know enough about the specific diagnosis to base my reply on that, so I am glad Gerry has commented.</p> <p>Firstly how is the cat in itself just now and how has it been over the past year? If it well and happy, there is a significant risk the cat will feel worse with treatment and given the long term prognosis is prob not great even with chemo, is that fair on the cat?</p> <p>You say the owner feels the lymph nodes have been enlarged for a year- well that doesn&#39;t fit with Dr Googles prognosis of 4-8 weeks</p> <p>Does the cat have any concurrent co-morbidities eg renal disease</p> <p>Why did it get septic arthritis??? Unless an obvious puncture wound, then this rings alarm bells- did the neutrophils look toxic on joint tap, I guess it could have been an inflammatory reaction rather than infection, (assume culture was done, but negative doesn&#39;t rule out infection) but even so......</p> <p>What is the cat&#39;s temperament like?</p> <p>Is the owner&nbsp;REALLY fully&nbsp;aware of what chemotherapy entails? What she will be putting her cat through at 15 years of age? (Doesn&#39;t mean I think it is wrong full stop, but needs to be an appropriate case)</p> <p>Regarding protocols, my understanding is that there is no evidence that shows that one protocol for lymphoma is better than another, so I base my choice on costs/cat&#39;s suitability/temperament, but waiting for further typing wouldn&#39;t affect my choice (or should it <a href="/members/gerrypolton" class="internal-link view-user-profile">Gerry Polton</a>not nec talking about this case, more a general question)</p> <p>Out of interest Gerry, what did you base your decision on?</p><div style="clear:both;"></div>RE: Cat with multicentric b cell lymphomahttps://www.vetsurgeon.org/thread/148447?ContentTypeID=1Mon, 07 Dec 2015 08:25:06 GMT146601cc-3922-4be7-9974-7e1d4e45a66b:d107375e-704d-4dee-bad9-012f6b3e1386Gerry Polton<p>It&#39;s always hard to judge without seeing a case but I have a feeling that I would not treat this case with chemotherapy (or steroids) at all.</p> <p>Gerry</p><div style="clear:both;"></div>