Canine Stomatitis

RE: Canine Stomatitis

Evelyn Barbour-Hill — Thu, 10 Dec 2015 02:52:50 GMT

[quote user="Julian Earl"]Stomatititis = Halitosis hell so antibiosis of some descriptionas well.[/quote]

I honestly don't understand that. Halitosis is only a problem for the owner, not the dog.

RE: Canine Stomatitis

Julian Earl — Wed, 09 Dec 2015 20:37:31 GMT

I've seen chronic stomatitis in Staffs that only responded to Stomorgyl and Preds, [ YES, I KNOW!!!.] and client communication is critical re.the chronicity. I think a punch biopsy would be safer than wedge but biopsy has to be the way to go. On principle, apply dental hygiene as with cats, measures, and consider auto-immunity I think. Stomatitis must be very painful surely, so anti-inflammatories are essential. Stomatititis = Halitosis hell so antibiosis of some descriptionas well. HTH?

RE: Canine Stomatitis

Iain McAllister — Wed, 09 Dec 2015 17:39:41 GMT

yes eating - pain difficult to assess... any ulceration in the mouth has got to be uncomfortable tho...

RE: Canine Stomatitis

Hannah Wynne Richards — Wed, 09 Dec 2015 17:28:48 GMT

Is it eating normally, and does it seem to have any oral pain?

Wynne

RE: Canine Stomatitis

Iain McAllister — Wed, 09 Dec 2015 11:07:33 GMT

Update on this - had been on antirobe post dental - I changed to stomorgyl and the drooling and bleeding has resolved - latest pic below Also did a coag screen and haematology

Questions -

1. with the abnormalities in the coag screen what would be the advisability of biopsy

2. with the appearance of the tissues would I get a meaningful result as it looks ulcerated and I know this can make interpretation difficult

Prothrombin Time 7.4 seconds 6.0 - 11.0

Partial Thromboplastin 30.2 12.0 - 24.0 High

Fibrinogen (Citrate) 4.6 High g/L 1.0 - 4.0

HAEMATOLOGY

Red cells 6.85 10^12/L 5.50 - 8.50

Haemoglobin 15.3 g/dL 12.0 - 18.0

Hct 0.458 l/L 0.380 - 0.570

MCV 66.9 fL 61.0 - 80.0

MCH 22.3 pg 20.0 - 26.0

MCHC 33.4 g/dL 30.0 - 36.0

Absolute retic. count 96.6 10^9/L <=110.0

White Cells 20.5 High 10^9/L 6.0 - 15.0

Neutrophils (Absolute) 12.92 High 10^9/L 2.50 - 12.5

Band neutrophils High 10^9/L(Absolute) 0.41 0.00 - 0.40

Lymphocytes (Absolute) 3.08 10^9/L 1.40 - 4.90

Monocytes (Absolute) 2.67 High 10^9/L <=0.8

Eosinophils (Absolute) 1.44 10^9/L 0.00 - 1.60

Nucleated RBC 10^9/L(Absolute)0.21

Platelet count 86 Low 10^9/L 150 - 450

Red cells appear normal.

Small platelet clumps seen. Platelet count should be considered

minimum value.Increased anisothrombia with both populations of normal and

macrothrombocytes seen. Presence of macrothrombocytes may be

acceptable for CKCS breed.

RE: Canine Stomatitis

Virginia Campbell — Sat, 05 Dec 2015 02:24:01 GMT

From what I can gather, in times of RBC destruction, reticulocytes get out of the bone marrow into circulation and do the best they can to help even though they're babies. In times of platelet destruction, young platelets sit in the bone marrow dressing room putting on their makeup and protesting that they're not ready yet. Vincristine (dunno if same effect as vinblastine) kicks them out on stage to get on with the show. So used in emergency if circulating platelets are dangerously low, to stop the dog dying before the pred has a chance to work. Although the speaker last night quoted a paper which showed faster recovery times to discharge from hospital in IMTP dogs that got pred plus vincristine versus pred alone, so that suggested it's a good idea to use in IMTP even if platelets aren't frighteningly low/clinical signs petechiae etc like in Martin's case.

RE: Canine Stomatitis

Nicola Cole — Fri, 04 Dec 2015 20:04:11 GMT

Was the vinblastine used due to the severity of the condition or would you advocate this for AITP or AIHA full stop? I've only ever used oral meds for these cases...should I be using injectables to kick start things instead?

RE: Canine Stomatitis

Martin Atkinson — Fri, 04 Dec 2015 18:25:57 GMT

[quote user="Virginia Campbell"]I didn't actually know this about CKCS by the way, I learned it at a clotting disorder talk last night. [/quote]I did but when I had a CKCS with petechial haemorrhages, a PCV of 16 and a platelet count of 2x10^9/l I figured it was more than just large platelets responsible for the low count!

I resurrected it overnight with a shot of vinblastine and it made a full recovery after a few weeks of preds. The history fitted an iatrogenically induced AITP as it occurred just 2 weeks after a booster.

Sorry for the tangent.

RE: Canine Stomatitis

Virginia Campbell — Fri, 04 Dec 2015 16:25:11 GMT

[quote user="Martin Atkinson"]I don't like the amount of blood involved, the lesions look like purpura in the photograph, and would and want to do a cbc and mucosal clotting time if not a coagulation profile before I chopped bits out of its pharynx. Cavaliers like getting AITP and AHA![/quote]

Good idea. Bear in mind that CKCS also can have few but large platelets as a normal feature (these fewer big platelets work just as well as more numerous small ones) so don't panic if PLT count is low, just need to look at a smear to check (well I'd send a smear off as I wouldn't be confident to identify megakaryocytes and declare them normal. I like sending stuff off cos when I get the results I can ring the lab and sponge off the pathologists' superior knowledge). I didn't actually know this about CKCS by the way, I learned it at a clotting disorder talk last night.

RE: Canine Stomatitis

Rob Davis — Fri, 04 Dec 2015 12:45:30 GMT

[quote user="villagevet"]Both also had evidence of Simonsiella[/quote]

Is this not considered at normal oral resident?

RE: Canine Stomatitis

Lindsey Edwards — Fri, 04 Dec 2015 00:40:17 GMT

I would do a scrape and cytology first-have met grossly identical lesion and similar history in ckcs twice. Both eosinophilic, one on serology reactive to pollens and dust mites, second not tested. Both responded completely to atopic type treatment schedule and maintained symptom free on hydrolysed diet. Was afraid to biopsy first due to bleeding risk and access, cytology on both clearly suggestive of hypersensitivity. Both also had evidence of Simonsiella

RE: Canine Stomatitis

Rob Davis — Thu, 03 Dec 2015 19:43:29 GMT

I agree with Martin that I would be wanting to check clotting parameters before cutting anything.

RE: Canine Stomatitis

Martin Atkinson — Thu, 03 Dec 2015 18:55:57 GMT

I don't think you have much choice but to biopsy but I don't like the amount of blood involved, the lesions look like purpura in the photograph, and would and want to do a cbc and mucosal clotting time if not a coagulation profile before I chopped bits out of its pharynx. Cavaliers like getting AITP and AHA!