Guinea pig ovarian cyst treatment

RE: Guinea pig ovarian cyst treatment

Michael Woodhouse — Tue, 19 Dec 2017 22:36:58 GMT

[quote user="Mark Rowland"]GnRH analogues don't work because of the variable cell lines these cysts can be derived from.[/quote]

As in, you believe that guinea pig LH surge is not mediated by GnRH as it is in other species (Receptal [GnRH] is licensed in diverse species from cows to rabbits and even rainbow trout) or something else? Guinea pig GnRH is different to that in pretty much all other mammals and fish?

[quote user="Mark Rowland"]chorulon is the way to go[/quote]

Which is having a very specific LH like activity and seems at odds with the reasoning for not using GnRH.

I'm also interested in the deaths from needle drainage. I've drained lots in cows over the years and agree that some just re-form, but if done carefully I see it as a very low risk procedure. I'd hope a vet (perhaps with ultrasound guidance) could perform better than a lay rodentologist! In cows I've used in in cysts seemingly refractory to hormonal treatment (my theory is no LH receptors, but I can't prove that).

I'm not being an arse, I just find reproductive physiology fascinating!

RE: Guinea pig ovarian cyst treatment

grumpyoldman — Tue, 19 Dec 2017 19:46:40 GMT

I have drained them percutaneously , nothing much happened they just refilled really quickly, spayed a few ,they did fine, may try the LH in future. The flank o hyst also sounds like a very good idea.

RE: Guinea pig ovarian cyst treatment

Mark Rowland — Tue, 19 Dec 2017 15:59:35 GMT

Don't stick needles into G pigs to pop cysts.

Ive had dead G pigs from rodentologists who do that.

To answer your question, GnRH analogues don't work because of the variable cell lines these cysts can be derived from.

If OHE isn't an option (and most pigs with active cysts have a degree of cystic endometrial hyperplasia) then chorulon is the way to go.

Ive popped one or two accidentally and they haven't died. Im not a big squeezer of g pig abdomens though

Good luck

RE: Guinea pig ovarian cyst treatment

vetbl.locum — Thu, 14 Dec 2017 15:06:54 GMT

Thanks

Never tried to rupture them but if burst when rectal ling never worried that much.

Some older farmers(and vets)claimed rupture was better than GnRH

RGds

RE: Guinea pig ovarian cyst treatment

Michael Woodhouse — Wed, 13 Dec 2017 23:51:40 GMT

[quote user="vetbl.locum"]PS Do vets still manually rupture cysts in cows these days ?[/quote]

It's gone full circle. School of thought was may cause bursa adhesions but no real evidence and remember the follicle ruptures in the normal ovulation process. I'm happy giving a firm but gentle squeeze and see what happens. Difficult to qualify but I'm eating a satsuma and the force compresses it but doesn't rupture the skin. Otherwise treat with P4/GnRH.

RE: Guinea pig ovarian cyst treatment

vetbl.locum — Wed, 13 Dec 2017 21:41:22 GMT

Just a random thought:

Would there be any benefit from precutaneously draining cyst ( guided by ultrasound ? ) then GnRH injection?

Rgds

PS Do vets still manually rupture cysts in cows these days ?

RE: Guinea pig ovarian cyst treatment

Lucy Fleming — Wed, 13 Dec 2017 00:01:12 GMT

Bumping an old thread as saw a GP with a large palpable ovarian cyst today (or appeared so at least, on a very quick, no clipping, in the middle of a 10 min consult scan) - have discussed surgery with the owners but they are not really inclined (elderly-ish GP, and it is a fairly spectacularly large cyst) but would probably be keen to try medical treatment. Anyone have any experience of using GnRH for these, compared to hCG?

RE: Guinea pig ovarian cyst treatment

Gillian Mostyn — Tue, 27 Oct 2015 15:23:13 GMT

Thanks Marie

RE: Guinea pig ovarian cyst treatment

Marie Kubiak — Tue, 27 Oct 2015 14:17:40 GMT

As well as medical treatment, discuss flank ovariectomy with them as an alternative to ovariohysterectomy if surgical risk is their main sticking point. If you do get to scan it, uterus is fine and ovarian pathology is confirmed then this is a much easier approach and GPs seem to cope better with surgery as it is quicker and they can remain in ventral recumbency. Being guinea pigs they still can be high maintenance post-op patients but do far better than those who have midline OVH.

Marie

RE: Guinea pig ovarian cyst treatment

Glenn Hodgson — Mon, 26 Oct 2015 21:59:36 GMT

[quote user="Michael Woodhouse"]

I'm guessing you are not giving it IV as we do in cows...............

[/quote]

Yup, And don't give all of itt. :-)

RE: Guinea pig ovarian cyst treatment

Gillian Mostyn — Mon, 26 Oct 2015 21:42:23 GMT

Thanks!

RE: Guinea pig ovarian cyst treatment

Michael Woodhouse — Mon, 26 Oct 2015 20:36:43 GMT

I'm guessing you are not giving it IV as we do in cows...............

RE: Guinea pig ovarian cyst treatment

Catriona MacIntyre — Mon, 26 Oct 2015 20:14:46 GMT

+1 for Chorulon. Works well.... but beware, it is a very stingy jag and the piggy with squeeeeeeel!

RE: Guinea pig ovarian cyst treatment

Glenn Hodgson — Mon, 26 Oct 2015 18:59:41 GMT

Corulon sc every 3 weeks for 3 occasions often helps,. the benefits last often.' a while', sometimes ages. I'll very occasionally drain really big ones if mot allowed to remove. Cant remember dose offhand.

You can usually palpate these very easily. Often around1-3 cm.1

RE: Guinea pig ovarian cyst treatment

Gillian Mostyn — Mon, 26 Oct 2015 16:39:53 GMT

All valid questions - but I can't answer them as I haven't seen this GP yet! I would certainly discuss the likelihood of other problems causing the symptoms (I'm actually convinced that the GP has become ill too quickly for it to be cysts - would rule out dental disease etc first) and there would be risks of uterine disease too unless spayed.

RE: Guinea pig ovarian cyst treatment

Anthony Dennison — Mon, 26 Oct 2015 16:14:25 GMT

[quote user="Gillian Mostyn"]this owner definitely doesn't want their GP to have any surgery[/quote]

Did she say why? Could you approach it like a cow; prostaglandins etc.

Anecdote; I spayed a dog with a pyo that had a history of flank alopecia. Turned out to have bilateral ovarian carcinoma. Has the pig been scanned to confirm ovaries are cystic and not solid.

Sorry, more questions than answers but might stimulate some discussion!