https://www.vetsurgeon.org/f/clinical-questions/23425/medicine for a patient with acute Kidney disease with elevated BUN and Creatinine can be recovered by giving IV N-acetyl cysteine? this is open for the discussion? en-USTelligent Community 10https://www.vetsurgeon.org/thread/145575?ContentTypeID=1Fri, 23 Oct 2015 08:57:21 GMT146601cc-3922-4be7-9974-7e1d4e45a66b:685216de-2c29-4e90-8b9b-bfedb6dc3632Sammy82<p>ACC is useful to treat NSAID toxicity, so might have some indirect benefits if the kidney failure is caused by this. It works by delivering building blocks for Gluthation, which is an essential part of the Cytochrom-P450-System in the liver. So giving ACC might help the liver metabolism along, I am not sure of any effect on the kidneys directly. It works better given orally, as then 100% will end up in the liver where it is needed. (source: The Small Animal Veterinary Nerdbook by Sophia Yin)</p><div style="clear:both;"></div>