Osurnia

RE: Osurnia

Martin Atkinson — Thu, 01 Oct 2015 11:00:50 GMT

[quote user="Catriona MacIntyre"]It is important that the ear canal is really thoroughly cleaned,[/quote]I think this is something that is underestimated. Pseudomonas particularly produces slimy stuff which forms a protective shield and is probably one of the reasons why conventional therapy fails even if culture says it's sensitive to the antibiotic you're using. A quick flush may therefore not be enough to shift it. Also, AFAIK Osurnia is water based so that if you do have to flush again it is easier to shift out than some previous similar product which was lanolin based.

RE: Osurnia

Aine Seavers — Thu, 01 Oct 2015 00:57:43 GMT

Any concerns about the prolonged use of bethemethasone in these patients>- the drug companies data sheet on acth shows an effect-my personal observations would be that as vets stopped using bethameth , the incidence of cushinoid cases dropped to virtually nil, that a lot of the bad press for glucocorticoids came from this drug and hardly any with preds so now we do use g.c with less angst in cases that really benefit from g/c-

anyone use this ear prep in an dog already on nsaids for say arthritis and then had an issue given the systemic absorption of this ear drops?

Specialist here uses Easotic daily for 10 days in severe cases- if we are sharing off label uses:-)

Cortavance has a glycol base and stings a lot less than many g/c creams- plus lamisil sets up a burning hot reaction after 10mins which can be painful-the bethameth would stop that in this case but good to be aware of if ever using it neat on one of our patients-learnt that from a client who wondered about her dog's delayed agitation after she home treated with lamisil so she used it on herself.

RE: Osurnia

Michael Woodhouse — Wed, 30 Sep 2015 23:35:03 GMT

[quote user="Catriona MacIntyre"]Happy about putting florfenicol into an ear.... hmmmm, no, not really. But, on the other hand, I think this is better than other antibiotics being used inadequately and ending up with an end stage ear and resistant bacteria.[/quote]

I wouldn't worry - one dose for a 100kg calf with pneumonia equals 200 dog treatments. The product is available as an in feed preparation for pigs.

If we get resistance, you putting 10mg into an ear is nothing!

RE: Osurnia

Stephen Courtney — Wed, 30 Sep 2015 22:08:14 GMT

[quote user="cathal rafferty"]

Haven't tried it yet but we had the rep in giving the presentation during the week. I can see the convenience and potential for much better compliance but i've concerns about using such a novel antibiotic as florfenicol as a first line treatment, which is what was being suggested. What do others think?

I can't understand why no company will come up with a topical steroid a la cortavance for ears. Seems we'd control a lot of atopic otitis without need for antibiotics at all...

[/quote]

For the purely inflamed OE cases, you can either use cortvance straight into the ear, about 0.5ml daily for a week, then alternate days - or spike a bottle of ear cleaner with dexadreson - Sue P recommended 2ml per 100ml ear cleaner - and use that 2-3 times a week.

It often works really well.

however the cortavance will sting if there are ulcerated areas along the canal.

I completely agree that powerful and special antibiotics should not be bundled with the steroids - what i would give for posatex without the antimicrobials!

RE: Osurnia

cathal rafferty — Wed, 30 Sep 2015 22:00:15 GMT

I can't understand why no company will come up with a topical steroid a la cortavance for ears. Seems we'd control a lot of atopic otitis without need for antibiotics at all...

RE: Osurnia

Catriona MacIntyre — Wed, 30 Sep 2015 20:47:07 GMT

I have used it in a case where the dog had such severe behavioural problems that it could not be medicated by the owners, or even muzzled for sedation!

It is important that the ear canal is really thoroughly cleaned, and the tympanic membrane checked. I took cytology samples then flushed with warmed saline (about 500ml as far as I remember) then Epiotic, then more saline (maybe over the top but I was having difficulty shifting the grey soft stuff near the eardrum), then as far as possible dried it out carefully and applied the Osurnia. I also gave an IV dose of dexamethasone straight afterwards (I think I got this from a Sue Paterson article on using ear wicks) to reduce some of the inflammation associated with flushing.

He was anaesthetised a week later, the canal checked (but not flushed, as per instructions) and the next vial applied, then another 2 weeks before GA, recheck and repeat cytology.

The dog is undergoing behavioural therapy (APBC registered behaviourist) to enable the owners to eventually fit a muzzle successfully themselves and then work on allowing his ears to be handled whilst conscious. He has alprazolam before and after each visit to the surgery to try and reduce the chances of him building up a bad association with us or the premises. Sedating him, quite frankly is horrible and stressful for both us and him. So far this does seem to be working well and he loves to visit.

Happy about putting florfenicol into an ear.... hmmmm, no, not really. But, on the other hand, I think this is better than other antibiotics being used inadequately and ending up with an end stage ear and resistant bacteria.

RE: Osurnia

Rob Loxley — Wed, 30 Sep 2015 13:49:02 GMT

Re cleaning, official advice is saline before each application and not in between. Obviously for those 'exudative ears' it may not be the best option

RE: Osurnia

patrick murphy — Wed, 30 Sep 2015 13:36:16 GMT

my question , what about cleaning in an actively inflamed/infected ear?

RE: Osurnia

stuart mcmorrow — Tue, 29 Sep 2015 22:26:54 GMT

I used it on my first case last week. A dog with one sore ear and owner couldn't get drops in.

Saw it back last night and put the other tube and and so far seems pretty good. So I'll definitely be ordering some more in.

RE: Osurnia

Rob Loxley — Tue, 29 Sep 2015 22:23:54 GMT

If you have bilateral OE do you need one tube PER ear and repeat - if so more pricey - but otherwise looks interesting. Certainly Lamisil was always great for fungal/yeast infections in people

RE: Osurnia

Linda Filshie — Tue, 29 Sep 2015 20:27:42 GMT

Have ordered some in - now waiting with breathless anticipation for a suitable case to try it on...

RE: Osurnia

Emily Rainbow — Tue, 29 Sep 2015 18:04:35 GMT

Will also be following this with interest. Not had the rep in yet to question but it sounds too good to be true!

RE: Osurnia

peter chalkley — Tue, 29 Sep 2015 17:39:30 GMT

*USELESS ANSWER ON THE WAY*

I have tried it in my first case today, I spoke to the rep at length and frankly wont believe it until I use it because their sell on it sounds excellent.

I can report that the dog shook its head straight after application and nothing came out. the dog also appeared to be soothed by the application, lets see what happens in a week!!