https://www.vetsurgeon.org/f/clinical-questions/23172/seizure-episode-after-carprofen Posting on behalf of a colleague dealing with a difficult client. 13 y.o. border collie, stiff and sore with OA. Was started on carprofen, and after 4 days had a single seizure like episode. Owner then went on google, has then decided it was the NSAIDen-USTelligent Community 10https://www.vetsurgeon.org/thread/141298?ContentTypeID=1Mon, 10 Aug 2015 20:26:19 GMT146601cc-3922-4be7-9974-7e1d4e45a66b:9a411933-5229-4b54-980f-8c86ab39ef55Joyce Whitehead<p>+ 1 for Pardale. Although with this sort of client I&#39;d be doing a blood screen to rule out any liver disease before starting a paracetomol based drug, as Sod&#39;s law would suguest it will get something else...</p><div style="clear:both;"></div>https://www.vetsurgeon.org/thread/141297?ContentTypeID=1Mon, 10 Aug 2015 19:50:25 GMT146601cc-3922-4be7-9974-7e1d4e45a66b:3f7292f4-9bc2-41fe-b1d4-a73ba0b49593Charlotte Marshall<p>Or good old fashioned plt!</p><div style="clear:both;"></div>https://www.vetsurgeon.org/thread/141294?ContentTypeID=1Mon, 10 Aug 2015 19:35:05 GMT146601cc-3922-4be7-9974-7e1d4e45a66b:30c5e3e7-11e1-4c06-86f0-07f0f13d8214Michael Woodhouse<p>Pardale V is not an NSAID and can make a huge difference to some dogs.</p><div style="clear:both;"></div>https://www.vetsurgeon.org/thread/141290?ContentTypeID=1Mon, 10 Aug 2015 18:59:47 GMT146601cc-3922-4be7-9974-7e1d4e45a66b:1d813f2f-0c17-4e05-87b2-ae92deca7650Robin Grimmer<p>You can&#39;t really blame the owner for coming to the probably wrong conclusion that the nsaid was to blame, but &nbsp;If the owner is really anti nsaid now you could try tramadol.</p><div style="clear:both;"></div>https://www.vetsurgeon.org/thread/141287?ContentTypeID=1Mon, 10 Aug 2015 18:21:28 GMT146601cc-3922-4be7-9974-7e1d4e45a66b:63ab6460-f97c-4cb2-b75f-fc307f80059cMartin Atkinson<p>I would tell the owner that there is no known such side effect but it might be a good idea to investigate medical reasons for the seizures. &nbsp;I would then tell them that they have a choice: have a lame dog in chronic pain or risk the infinitesimally small chance that the carprofen had anything to do with it. However if I was feeling more magnanimous I might suggest a course of Cartrophen - but then it may have a fatal haemorrhage due the platelet suppression. Can&#39;t win with these people I&#39;m afraid.</p><div style="clear:both;"></div>