Cisapride use in cats?

RE: Cisapride use in cats?

Joyce Whitehead — Sat, 01 Aug 2015 17:50:31 GMT

I've only tried cisapride in dysautonomia cases, which unfairly to the drug means it didn't have much effect. But I'd strongly second the use of Movicol, the plain sachets are really easy to get cats to take and really effective. We also start with about 1/8 teaspoon (or a decent pinch) twice daily and titrate up depending on effect.

It has transrormed the lives of several of our feline patients, and their owner too come to that...

No side effects seen here at all.

RE: Cisapride use in cats?

Stephen Courtney — Sat, 01 Aug 2015 16:27:48 GMT

I have used cisapride in cats several times with no side effects.

The drug was pulled in the US because obese folk with multiple health issues including toilet problems had heart attacks and the drug was blamed.

Possibly unfairly considering the typical user demographic....

RE: Cisapride use in cats?

Danny cazabon — Sat, 01 Aug 2015 15:37:21 GMT

Yes,

I have decided to check with him on Monday.

Thank you.

RE: Cisapride use in cats?

Rob Loxley — Sat, 01 Aug 2015 13:21:55 GMT

Have successfully used cisapride in cats, likewise other cases well managed on lactulose. As for whether to steer clear with cardiac isssues I'd ask your cardiologist

RE: Cisapride use in cats?

ruths — Sat, 01 Aug 2015 13:02:10 GMT

I've used it with no sode effects in cats

but I haven't knowingly used it in a cardiac case

RE: Cisapride use in cats?

Utlendigur — Fri, 31 Jul 2015 21:12:58 GMT

I've used cisapride once - in a very elderly cat that was on lactulose, but still getting massively constipated and starting to look like it was developing megacolon. It was needing enemas every few days - not ideal to have to keep giving GA or heavy sedation in such an old cat, and was verging on PTS. It seemed to work - the cat is still going 4-5 months later and hasn't had an enema since.

RE: Cisapride use in cats?

Danny cazabon — Fri, 31 Jul 2015 20:53:02 GMT

Thank you both for your help

Much appreciated,

Danielle

RE: Cisapride use in cats?

Andrew Henfrey — Fri, 31 Jul 2015 20:31:57 GMT

No side effects to see. Full bloods about 3 months ago were normal.

RE: Cisapride use in cats?

Dagmar Steele — Fri, 31 Jul 2015 20:31:39 GMT

[quote user="Danielle Dillon"]

Hello,

Thanks for your reply. How often would you give it to a patient and at the same dosage that's in the BSAVA small animal formulary, it's under bowel cleansing solution: cats prior to lower GI exam 22-33ml/kg po?

[/quote]

Rather not I think. We get sachets (Movicol junior) in Germany and I have the owner taper it to the cats needs. Mostly I'll give a quarter of a tea spoon twice daily, in small cats I start with 1/8 of a tea spoon, some cats will need up to half a teaspoon bid. Do not use the products with added electrolytes in cats with CRI.

RE: Cisapride use in cats?

Danny cazabon — Fri, 31 Jul 2015 20:20:38 GMT

Oh, ok, very good. Do you find there are any side effects in your case?

RE: Cisapride use in cats?

Andrew Henfrey — Fri, 31 Jul 2015 20:14:31 GMT

I use Cisapride on my own 16 year old cat for a chronic constipation tendency secondary to lumbosacral disease. He originally went on lactulose but it was increasingly difficult to get him to eat it. He has been on Cisapride 5mg bid [5kg cat] for about a year now and although his hindlegs are getting progressively worse with the LS problem, he has only required one enema since starting. I crush it and mix it with butter.

A vet friend has her small cat on cisapride 2.5mg bid for megacolon, again for over a year.

I recall there was BSAVA Congress session from 2014[?] which I listened to as a podcast which was useful.

RE: Cisapride use in cats?

Danny cazabon — Fri, 31 Jul 2015 20:09:06 GMT

Hello,

RE: Cisapride use in cats?

Dagmar Steele — Fri, 31 Jul 2015 19:59:13 GMT

I'm of no help re the Cisapride I'm afraid but have to say I do see much better results in chronic constipation in cats with Macrogol than with Lactulose!