stomach ulceration treatment - now antepsin is like hens teeth

RE: stomach ulceration treatment - now antepsin is like hens teeth

Stephen Courtney — Mon, 03 Aug 2015 14:25:22 GMT

Cats are not on the license for apoquel, and Zoetis will NOT give you the nod to use it. At least not the last time I looked!

No it isn't OK. Someone will have to be the first to try it, like cerenia, but it won't be me!

RE: stomach ulceration treatment - now antepsin is like hens teeth

Michael Woodhouse — Sun, 02 Aug 2015 23:05:42 GMT

[quote user="Stephen Courtney"]

There is at least one error in the BSAVA formulary, in that it gives a feline dose rate for Apoquel

Given the vast amount of information in it, I would not be surprised if there were other errors too.

[/quote]

I was speaking to a vet the other day using the product in cats, having spoken to the manufacturer. Is this not ok?

RE: stomach ulceration treatment - now antepsin is like hens teeth

Stephen Courtney — Sun, 02 Aug 2015 21:42:00 GMT

There is at least one error in the BSAVA formulary, in that it gives a feline dose rate for Apoquel

Given the vast amount of information in it, I would not be surprised if there were other errors too.

RE: stomach ulceration treatment - now antepsin is like hens teeth

Martin Atkinson — Sat, 01 Aug 2015 09:10:23 GMT

[quote user="Noweia"]

Looked up De-Noltab, this is from the Patient Information Leaflet:

[quote]When De-Noltab tablets enter the stomach or intestine the tablet breaks up and coats the ulcer. It forms a protective barrier which protects the ulcer from the stomach acid, giving it time to heal. This protective layer stays in place during your meal but needs renewing before the next meal.[/quote]

[/quote]Read the information in the BSAVA Formulary, it is a little different!

RE: stomach ulceration treatment - now antepsin is like hens teeth

Noweia — Fri, 31 Jul 2015 23:37:07 GMT

Looked up De-Noltab, this is from the Patient Information Leaflet:

Andrew, what dose did you use for your case?

RE: stomach ulceration treatment - now antepsin is like hens teeth

Luca Poddighe — Fri, 31 Jul 2015 14:49:38 GMT

[quote user="Sorrel Proctor"]We're trying out Maalox, although haven't used it enough to have an opinion on efficacy yet, anyone else?[/quote]

Again is an antiacid treatment, Ma++ and Al+ hydroxide, so it will have no direct effect on an active gastric bleeding. It may help preventing any worsening.

RE: stomach ulceration treatment - now antepsin is like hens teeth

Sorrel Proctor — Fri, 31 Jul 2015 13:36:20 GMT

We're trying out Maalox, although haven't used it enough to have an opinion on efficacy yet, anyone else?

I hadn't heard of De-Noltab before either but will bear in mind!

RE: stomach ulceration treatment - now antepsin is like hens teeth

Noweia — Thu, 30 Jul 2015 20:44:40 GMT

[quote user="Dagmar Steele"]

Anyone using Famotidine, can you get it?

[/quote]

We have the 20mg tabelts in stock, think we get ours from Henry Schein?

RE: stomach ulceration treatment - now antepsin is like hens teeth

Martin Atkinson — Thu, 30 Jul 2015 10:31:57 GMT

[quote user="Dagmar Steele"]

Anyone using Famotidine, can you get it?

[/quote]I'm not but you can get it from Summit Veterinary as a 5mg tablet.

RE: stomach ulceration treatment - now antepsin is like hens teeth

Dagmar Steele — Thu, 30 Jul 2015 10:04:19 GMT

Anyone using Famotidine, can you get it?

RE: stomach ulceration treatment - now antepsin is like hens teeth

Kate Richardson — Thu, 30 Jul 2015 09:28:57 GMT

Cross ref to the thread on cat with chronic renal disease/pancreatitis- hope David doesn't mind me copying and pasteing:

"Ranitidine according to studies needs to be used at 4mg/kg at least to change stomach pH. At 2mg/kg it is no better than placebo. Omeprazole needs about 7d to reach maximal effect. Best given in evening as proton pumps manufactured during the overnight fast.

Agree re metoclop - next to useless in cats, they have minimal dopamine recpetors. In fact, it's pretty crap in dogs too. Most hospitalised cats given metoclop don't vomit because of environmental stressors, not because they've had metoclop. In some vomting studies doens't perform any better than saline!"

We have got sucralfate here, both tablets and suspension, I can ask where we obtain it from.

Totally agree re gaviscon- I get oesophageal reflux occasionally which is unbelievably painful- gaviscon doesn't touch it, in fact nothing I have tried so far seems to, so any suggestionsgratefully recieved!

RE: stomach ulceration treatment - now antepsin is like hens teeth

Wren — Thu, 30 Jul 2015 09:24:44 GMT

I have been getting Sucralfate for horses on an STC via Idis. Quick and straight forwards, if a little pricey. Although that's probably not so much of a problem if you're not trying to dose for 500kg!

(Obviously not quick enough for the case above, but quick enough for us)

RE: stomach ulceration treatment - now antepsin is like hens teeth

Kara Gibson — Thu, 30 Jul 2015 09:09:54 GMT

I'm based in Hong Kong and we have a steady supply of sucralfate 500mg tablets called Sucari which is manufactured by a company called Jean-Marie Pharmacal Co., Ltd.

If any of you are able to import it then it may be worth a go to replace Antepsin until it comes back!

RE: stomach ulceration treatment - now antepsin is like hens teeth

David Mills — Thu, 30 Jul 2015 00:13:50 GMT

Gaviscon works differently. It is a mild antacid as well as sitting on top of the stomach material to prevent damage to mucosa if vomiting occurs. Sucralfate actively bound to inflamed/ulcerated areas. Gaviscon tastes awful for dogs (and worse for cats), and IMO is a pure placebo (has anyone ever taken it with a hangover? Doesn't work).

RE: stomach ulceration treatment - now antepsin is like hens teeth

Ashley Rubens — Wed, 29 Jul 2015 22:56:52 GMT

We've been using cytotec, no cases as dramatic as the OP but seems to be working, use as per BSAVA formulary.

RE: stomach ulceration treatment - now antepsin is like hens teeth

Catriona MacIntyre — Wed, 29 Jul 2015 22:18:12 GMT

[quote user="Linda Filshie"]

[quote user="Hannah Wynne Richards"]

Thanks. I'd never heard of De-noltab, so at least one of us is grateful to you.

Wynne

[/quote]

Likewise :)

[/quote]

Me three. I have been using IV omeprazole recently. Lasts 24hrs and I was told more effective at altering stomach pH than ranitidine (which is apparently a better prokinetic than it is anti-ulcer treatment)

RE: stomach ulceration treatment - now antepsin is like hens teeth

nikki — Wed, 29 Jul 2015 21:59:33 GMT

Has anyone any experience of using Gaviscon? Have had a few clients take it into their own hands to use instead of Antepsin and report good effects. Just wasn't sure if it was something I could be recommending.

RE: stomach ulceration treatment - now antepsin is like hens teeth

Martin Atkinson — Wed, 29 Jul 2015 15:25:45 GMT

[quote user="Andrew Mellor"]

....found but one had a tablet called De-noltab used in people for just that , it is a bismuth salt that seals ulcers ( other option Pepto-Bismol but no chance a dog was going to swallow that!)

[/quote]You're barking up the wrong tree here Andrew. Bismuth salts do not 'seal the ulcer' it works in human gastric ulcers because it is active against the Helicobacter and stimulates mucosal prostaglandin and bicarbonate secretion. In short it works against the causes of ulceration not the ulcer itself and doesn't act as barrier over the ulcer in the same way as the action of Sucralfate. You don't have to take my word for it, its in the BSAVA Formulary.

However, if anecdotal evidence suggests it is helpful then I wouldn't knock it. Just that given there is no evidence to link Helicobactor to gastric ulceration in our species it is not a direct substitute for sucralfate, AFAIA one does not exist.

RE: stomach ulceration treatment - now antepsin is like hens teeth

Joyce Whitehead — Wed, 29 Jul 2015 12:31:39 GMT

Thanks, useful to know. Any idea what caused the severe ulceration?

RE: stomach ulceration treatment - now antepsin is like hens teeth

Linda Filshie — Wed, 29 Jul 2015 11:53:51 GMT

[quote user="Hannah Wynne Richards"]

Thanks. I'd never heard of De-noltab, so at least one of us is grateful to you.

Wynne

[/quote]

Likewise :)

RE: stomach ulceration treatment - now antepsin is like hens teeth

Hannah Wynne Richards — Wed, 29 Jul 2015 10:06:57 GMT

Thanks. I'd never heard of De-noltab, so at least one of us is grateful to you.

Wynne