https://www.vetsurgeon.org/f/clinical-questions/22727/advice-on-possible-adenocarcinoma-metastasis Hi I recently posted about my own dog Roma&#39;s rectal adenocarcinoma which several people helpfully replied to (10YO FN border collie, rectal adenocarcinoma removed successfully 3.5yrs ago and followed by carboplatin chemo, recent recurrence confirmeden-USTelligent Community 10https://www.vetsurgeon.org/thread/136905?ContentTypeID=1Mon, 01 Jun 2015 14:37:36 GMT146601cc-3922-4be7-9974-7e1d4e45a66b:e6fd55a4-f9de-4b15-a8fb-4f758414d3f4Daria McLennan<p>Thanks Gerry, that&#39;s what I&#39;m hoping, can&#39;t find a source of pain but am keeping her well analgesed.</p> <p>Daria.&nbsp;</p><div style="clear:both;"></div>https://www.vetsurgeon.org/thread/136873?ContentTypeID=1Mon, 01 Jun 2015 12:09:54 GMT146601cc-3922-4be7-9974-7e1d4e45a66b:4a2fc38e-066b-4ba3-a534-dad88aeb1927Gerry Polton<p>Hi Daria</p> <p>My thoughts centre around an assumption that the clinical signs reflect pyrexia/hyperthermia. This would then be most likely to be secondary to infection. Bacteraemia can arise due to the abnormal bowel. Since antibiotics were used in her management we cannot really explore this further. Otherwise she may be intermittently painful. That could be due to organ distension, bowel ulceration and inflammation or metastasis to a site which induces discomfort eg bone. Hopefully we are just dealing with a bacterial complaint which is more or less better now. Consider additional analgesia if you don&#39;t feel that she is otherwise responding completely.</p> <p>Gerry</p><div style="clear:both;"></div>