retriever with OA, GI upset on NSAIDs

Re: retriever with OA, GI upset on NSAIDs

Christopher Saul — Sun, 26 Apr 2015 10:45:17 GMT

I think that even for long term (off licence) use of paracetamol, one should use pardale v over generic paracetamol, due to the cascade. The exceptions being with very small dogs for whom accurate dosing of pardale would be impossible (in which case use paediatric syrup), or for those dogs with very a specific containdication for codeine (eg constipation), though to be honest I can't ever see the tiny codeine component causing any problems anyway Though it is acceptable to go against the cascade when there is genuine good clinical reason to do so, I can't think of any, other than those I've already mentioned .So I think the cascade stands and we must use pardale. Dose wise, we use 10- 15mg/kg.

Re: retriever with OA, GI upset on NSAIDs

rjhvet — Sun, 26 Apr 2015 09:41:29 GMT

Paracetomol , pardale only licenced for 5 days but can get consent for o/l use or use generic paracetomol alone , with o/l consent, can add in trmadol, gabapentin etc etc, we do sometimes use gastroprotectants, case dependent, licenced zitac ( ?? cimetidine ) or omeprozole o/l, purchase our generics from munro or summit or nova, all good. Or try a different nsaid.

Re: retriever with OA, GI upset on NSAIDs

Liz w — Sat, 25 Apr 2015 16:22:41 GMT

I know it's very much a 'marmite' topic on here, but how about trying acupuncture and then titrating the dose down if it does well. By the way bi-academy have quite a few webinars on osteoarthritis and analgesia at the moment if you're interested.

Re: retriever with OA, GI upset on NSAIDs

Lindsey Edwards — Sat, 25 Apr 2015 16:04:35 GMT

Presume you have him on j/d also many stabilise drug free on right diet

Re: retriever with OA, GI upset on NSAIDs

Neil Wheadon — Sat, 25 Apr 2015 15:37:33 GMT

PLT

I've had a few not enjoy the NSAID experience and one especially did really well

Neil

Re: retriever with OA, GI upset on NSAIDs

Rob Loxley — Sat, 25 Apr 2015 12:57:26 GMT

[quote user="Michael Woodhouse"]We use it at the licensed dose rate, but some get really worried and go for the tiny BASVA manual rate of 10mg/kg[/quote]

Short term (<5d) I use the licensed dose, but longterm go more for 10mg/kg BID too

Re: retriever with OA, GI upset on NSAIDs

Michael Woodhouse — Sat, 25 Apr 2015 12:29:44 GMT

Pardale V is marvellous stuff - we've had dogs on it for years. Always warm off licence etc. We also use it with other NSAIDs to good effect (like they do in people) again with a warning to the owner. We use it at the licensed dose rate, but some get really worried and go for the tiny BASVA manual rate of 10mg/kg.

We use quite a bit of Previcox in these dogs and are very happy with it. The cost has fallen over the years so it's not much more expensive. Sucralfate was the only true gasteroprotectant, and you can't get any.

Re: retriever with OA, GI upset on NSAIDs

Joyce Whitehead — Sat, 25 Apr 2015 12:03:07 GMT

We also have a few NSAID intolerant dogs on Pardale alone, and it seems pretty effective. The licence is for (I think) 5 days continuous use, but it is fine longer, as long as owner aware you are off licence. I've had very few reactions to it. We also have some dogs on gastroprotectant and NSAID.

Re: retriever with OA, GI upset on NSAIDs

Bob Russell — Sat, 25 Apr 2015 10:08:32 GMT

Let everything settle and try another NSAI. Not sure it has to be a newer one as different patients respond differently. Dogs with meloxicam problems can be good on carprofen. Despite the negative comments here about Trocoxil, recent work has indicated it is just as safe and effective as carprofen. Also don't forget poorly leg tablets (with a meal!).

I suggest every one is given with a reasonable meal.

Re: retriever with OA, GI upset on NSAIDs

Hannah Wynne Richards — Sat, 25 Apr 2015 09:43:40 GMT

Try some of the newer NSAIDs, or you may find a combination of cartrophen and nutraceuticals useful.

Wynne