https://www.vetsurgeon.org/f/clinical-questions/22268/pinschers-and-distemper-vaccination I&#39;ve got a German Pinscher coming in last thing today for it&#39;s booster vaccination, and notes say for it not to have distemper vacc, just Vanguard CPV-L. It had a fit after a full distemper vacc in 2009, since then hasn&#39;t had anything. A quick googleen-USTelligent Community 10https://www.vetsurgeon.org/thread/133795?ContentTypeID=1Fri, 17 Apr 2015 19:11:10 GMT146601cc-3922-4be7-9974-7e1d4e45a66b:a52d913c-31dd-4628-9d86-01cb7caadf22Martin Atkinson<p>I would be 99% certain the fit after vaccine was idiosyncratic. Describe the symptoms of distemper to the owners and ask which they&#39;d rather risk - then get them to sign the disclaimer!</p> <p>I can&#39;t remember how many Pinschers I&#39;ve vaccinated over the years but it must be many and I&#39;ve never seen a reaction yet.</p><div style="clear:both;"></div>https://www.vetsurgeon.org/thread/133787?ContentTypeID=1Fri, 17 Apr 2015 17:39:29 GMT146601cc-3922-4be7-9974-7e1d4e45a66b:725123d5-931b-4a36-a884-09bb2a5109e8Richard Carter<p>why? distemper is same family as measles and some vaccines even use measles to induce the distemper Abs - how many times have you been vaccinated against measles - every year, second year, once every 10 years? Get the owners to sign a disclaimer that due to known hypersensitivity they are aware the regime is off licence but is probably at low risk given that the disease incidence is negligible. The high risk diseases of parvo and lepto are being covered</p> <p>I thought most reactions were linked to the lepto component?.</p><div style="clear:both;"></div>