https://www.vetsurgeon.org/f/clinical-questions/20588/polydipsia-polyuria-in-a-rabbit Hiya, Just wanting to pick your brains about a young (just under a year old- if memory serves me) rabbit that lives with a companion rabbit who is a couple years older. The owner reports polydipsia and polyuria (not urinating in normal area in cageen-USTelligent Community 10https://www.vetsurgeon.org/thread/124060?ContentTypeID=1Thu, 06 Nov 2014 20:08:20 GMT146601cc-3922-4be7-9974-7e1d4e45a66b:d7e7304a-1c94-44db-bde7-e266e2c15786Marie Kubiak<p>The water intake does sound excessive (usually 100ml/kg/d) and more than could be explained by evaporative losses. Urea drop can relate to PU/PD but also altered caecal flora with a switch to urea metabolising bacteria if normal flora are altered (antibiotics, reduced food intake, acidosis...). Have you got electrolyte measurements?</p> <p>Low grade dental or bladder discomfort&nbsp; or reduced food intake can all be factors in increased water intake and I would look at dental evaluation under GA, plus imaging of the urinary tract as a baseline. Survey radiographs are a good tool for both ends! I&#39;d also consider keeping the rabbit in for a day beforehand and accurately measure water and food intake plus collect a repeat urine sample to recheck dipstick, SG and to evaluate sediment.</p> <p>Marie</p><div style="clear:both;"></div>https://www.vetsurgeon.org/thread/123994?ContentTypeID=1Thu, 06 Nov 2014 07:28:12 GMT146601cc-3922-4be7-9974-7e1d4e45a66b:baf3f919-171a-40eb-8b31-06d67d09de3cCatherineThomas<p>Was haematology done alongside the biochem? It&#39;s often helpful to at least get a smear assessed for cell morphology, particularly if done at a lab with exotic experience.</p><div style="clear:both;"></div>https://www.vetsurgeon.org/thread/123992?ContentTypeID=1Thu, 06 Nov 2014 07:21:16 GMT146601cc-3922-4be7-9974-7e1d4e45a66b:2a2e3b92-c5d1-4bd0-b3c4-3d8a7e1f1dfeCatherineThomas<p>Have you done e.cuniculi serology yet? That would be my next step along with ultrasound of abdomen and body and skull radiography plus full oral exam under sedation.</p><div style="clear:both;"></div>https://www.vetsurgeon.org/thread/123989?ContentTypeID=1Thu, 06 Nov 2014 00:30:13 GMT146601cc-3922-4be7-9974-7e1d4e45a66b:8f31344b-1c07-4e4f-8158-b8b460f5f7afLinda Filshie<p>What&#39;s the rest of the clinical exam like? <p> If I recall correctly, PUPD in rabbits can be 2ry to pain. Worth checking teeth/spine/joints and careful palpation of the abdomen at least. I&#39;m sure one of the more rabbit-savvy guys will be along with helpful suggestions shortly...<div style="clear:both;"></div>