https://www.vetsurgeon.org/f/clinical-questions/20301/ticks-on-rabbits Has anyone any experience with efficacy and safety of treatments for existing tick infestations in rabbits? en-USTelligent Community 10https://www.vetsurgeon.org/thread/122153?ContentTypeID=1Tue, 07 Oct 2014 11:32:44 GMT146601cc-3922-4be7-9974-7e1d4e45a66b:1c190215-831d-47a0-aa45-b6fe5d4b8ef9Bob Russell<p>Permethrin works well as a tick repellent. Activyl Tick Plus and Vectra 3D have worked brilliantly as tick products here in the New Forest. Permethrin based products are freely available for rabbits so would be my first choice!</p> <p>From Twycross Zoo:</p> <p><b>Acute toxicity data for permethrin</b></p> <ul> <li>Permethrin is moderately to practically non-toxic via the oral route, with a reported&nbsp;<a target='_blank' href="http://wildpro.twycrosszoo.org/S/00Ref/KeywordsContents/l/ld50.htm">LD₅₀</a>&nbsp;for technical permethrin in rats of 430 to 4000 mg/kg.</li> <li>Via the dermal route permethrin is slightly toxic, with a reported dermal&nbsp;<a target='_blank' href="http://wildpro.twycrosszoo.org/S/00Ref/KeywordsContents/l/ld50.htm">LD₅₀</a>&nbsp;in rats of over 4000 mg/kg, and in rabbits of greater than 2000 mg/kg.&nbsp;</li> <li>Permethrin caused mild irritation of both the intact and abraded skin of rabbits.&nbsp;</li> <li>Permethrin caused conjunctivitis when it was applied to the eyes.&nbsp;</li> <li>The 4-hour inhalation&nbsp;<a target='_blank' href="http://wildpro.twycrosszoo.org/S/00Ref/KeywordsContents/l/lc50.htm">LC₅₀</a>&nbsp;for rats was greater than 23.5 mg/L, indicating practically no inhalation toxicity.&nbsp;</li> <li>The toxicity of permethrin is dependent on the ratio of the isomers present; the cis-isomer being more toxic.</li> </ul><div style="clear:both;"></div>