https://www.vetsurgeon.org/f/clinical-questions/20093/kitten-quadHi there, I am on a charity neutering trip at the moment, and got to wondering if the &#39;kitten quad&#39; mix could have potential here rather than the traditional ketamine/xylazine mix the cats get IM via the crush cage. I am envisaging that it might be anen-USTelligent Community 10https://www.vetsurgeon.org/thread/120919?ContentTypeID=1Tue, 16 Sep 2014 16:37:11 GMT146601cc-3922-4be7-9974-7e1d4e45a66b:b2efbe18-c129-4993-8058-393bbfc67778emma_j<p>Are you out with GCWS?</p> <p>I&#39;ve done a few of their neutering clinics, and several others in different&nbsp;countries too. Agree that xylazine has a huge advantage in inducing vomiting in this population, a lot of them are not adequately starved.&nbsp;Also used xylazine as a premed in dogs on a different project, followed by i/v ket/diazepam induction &amp; maintenance. </p> <p>I think the quad protocol would be cost prohibitive in this situation I&#39;m afraid. The lay volunteers/charity organisers at GCWS are always very enthusiastic though!</p><div style="clear:both;"></div>https://www.vetsurgeon.org/thread/120918?ContentTypeID=1Tue, 16 Sep 2014 16:26:34 GMT146601cc-3922-4be7-9974-7e1d4e45a66b:0e8d9559-6378-4d06-bbe1-a11a091b9df3Yantha Smyth<p>I think it would be possible to source the other drugs but not entirely sure. There seems to be no problem getting ketamine, so I would expect the other drugs could be obtained via the same provider. I have seen the odd bottle of domitor at the &#39;surgery&#39; but it is not in routine use due to cost. The Greek lady that co-ordinates things is going to find out for me if available and what cost would be.</p><div style="clear:both;"></div>https://www.vetsurgeon.org/thread/120917?ContentTypeID=1Tue, 16 Sep 2014 16:25:30 GMT146601cc-3922-4be7-9974-7e1d4e45a66b:a8c0eac0-cb92-4ccd-a210-44b2eca3fe73Mark Hedberg<p>My concern about mixing would mainly be the Ketamine - short term I&#39;ve never had a problem, but pH of ketamine is 3, so I wonder if long term that would mess with the other drug stabilities. I have no evidence or any kind of proof (not even anecdote!) but this is an issue that comes to mind.</p> <p>&nbsp;</p><div style="clear:both;"></div>https://www.vetsurgeon.org/thread/120916?ContentTypeID=1Tue, 16 Sep 2014 16:22:25 GMT146601cc-3922-4be7-9974-7e1d4e45a66b:9a9b34ae-0cbf-45c1-8d35-0094deda3e5aBob Russell<p>Xylazine and Ketamine are generally cheap drugs so that may be a priority for the charity. I don&#39;t like the mix as an anaesthetic but did find it quite safe when it was in vogue!</p> <p>Not sure how much recollection the patients will have of events. Ketamine is pretty good at screwing up short term memory so may actually be beneficial!&nbsp;</p><div style="clear:both;"></div>https://www.vetsurgeon.org/thread/120915?ContentTypeID=1Tue, 16 Sep 2014 16:22:01 GMT146601cc-3922-4be7-9974-7e1d4e45a66b:5a0488c7-ef7f-464d-9e8c-6f0fdbd546b8Martin Atkinson<p>One of the nasty effects of xylazine is to induce vomiting which is an advantage in a population of cats which it is not possible to be sure they&#39;ve been starved. I often use it for ferals/charity spays but try to give it 20 mins before the ketamine so they can have a good chunder first!</p><div style="clear:both;"></div>https://www.vetsurgeon.org/thread/120914?ContentTypeID=1Tue, 16 Sep 2014 16:11:33 GMT146601cc-3922-4be7-9974-7e1d4e45a66b:4479cf17-7fca-4c98-a17a-0ed12eece584Andrew Kent<p>I would guess that a lot of those decisions are based on drug availability or cost - is medetomidine available there?</p><div style="clear:both;"></div>