https://www.vetsurgeon.org/f/clinical-questions/19731/feline-lymphocytic-cholangitis 11 year old castrated DLH presented a couple of months ago with weight loss and inappetance, bloods suggestive of hepatopathy. Had liver biopsy taken one month ago and report was as follows: DESCRIPTION: Liver biopsy x 1. Two sections were examineden-USTelligent Community 10https://www.vetsurgeon.org/thread/118530?ContentTypeID=1Thu, 31 Jul 2014 15:38:35 GMT146601cc-3922-4be7-9974-7e1d4e45a66b:06b3aa6f-aaf8-47b8-a342-b7fe0d464cc1Martin Atkinson<p>[quote user=&quot;emma_j&quot;]+ SAME-e [/quote]+1 for SAMe we use Samylin in tablet or granule form.&nbsp;</p> <p>I always tell my clients that cats with this condition fall into 3 catergories: those that fail to respond, those that get better and those that improve but then regress. Liken it to George Best&#39;s liver and they get the idea! You&#39;re doing the right stuff but do add in the SAMe but remember the prognosis is guarded at any stage.</p> <p>We had one recently, it unfortunately bled out from the liver biopsy and the owner didn&#39;t want further surgery/blood transfusions. We thought it would be a nailed on hepatic neoplasia but lab report was lymphocytic cholangitis and said guarded to poor prognosis so the owner felt vindicated.</p><div style="clear:both;"></div>https://www.vetsurgeon.org/thread/118500?ContentTypeID=1Thu, 31 Jul 2014 11:00:00 GMT146601cc-3922-4be7-9974-7e1d4e45a66b:e7591270-8118-4d45-9a37-51c35914f7c1emma_j<p>+1 for mirtazapine, would also consider addition of famotidine + SAME-e (we usually use denamarin)</p><div style="clear:both;"></div>https://www.vetsurgeon.org/thread/118447?ContentTypeID=1Wed, 30 Jul 2014 18:47:22 GMT146601cc-3922-4be7-9974-7e1d4e45a66b:ad503319-8b73-4ef3-a800-01afbbe5a6bfEmily Nightingale<p>Would you consider mirtazepine as an appetite stimulant?</p><div style="clear:both;"></div>