https://www.vetsurgeon.org/f/clinical-questions/18437/mast-cell-tumour-question-for-oncologists I&#39;ve just diagnosed a mast cell tumour on the thigh of a 3 year old ME Labrador by FNA. He was used as a stud dog recently and the pups are due in a couple of weeks. My client is someone who likes as much information as possible, and he would likeen-USTelligent Community 10https://www.vetsurgeon.org/thread/111382?ContentTypeID=1Sat, 29 Mar 2014 20:22:17 GMT146601cc-3922-4be7-9974-7e1d4e45a66b:393cd0d3-88a5-4e6c-abe6-ea8435a607d8tess<p>Thanks Gerry,</p> <p>Those were my thoughts also. His owner is sensible and we are probably going to castrate him when he comes in for his MCT surgery. </p><div style="clear:both;"></div>https://www.vetsurgeon.org/thread/111272?ContentTypeID=1Fri, 28 Mar 2014 16:59:34 GMT146601cc-3922-4be7-9974-7e1d4e45a66b:76db20a3-8d94-4e48-9015-4887c031b597Gerry Polton<p>Hi Tess</p> <p>I am not aware of any data to suggest that there is a direct familial risk of mast cell tumours in dogs. However, it is certainly true that particular breeds of dog are at higher risk than average for the development of mast cell tumours. At risk breeds include Labradors, as well as the breeds more well-known for mast cell tumours: boxers, Weimaraners, Boston terriers. There are no further tests that I can tell you about which will help your owner to understand whether there might be an additional&nbsp;heritable risk factor for the pups.</p> <p>I would be interested in the views of others here. if I was asked, I would not advise that this entire male is not bred from again. Mast cell tumours are relatively commonplace and there is no evidence (in my opinion) to suggest that this dog has a germline risk of mast cell tumour development. However, one could also argue that there is no evidence to suggest that he does not convey an increased risk, so prudence should advise against breeding. What are your opinions?</p> <p>Gerry</p><div style="clear:both;"></div>