Neurological symptoms in a cat post propofol anaesthesia

Re: Neurological symptoms in a cat post propofol anaesthesia

Yantha Smyth — Fri, 11 Oct 2013 07:27:06 GMT

I also was told about the 'propofol reaction' at an anaesthesia CPD meeting; the speaker described the characteristic signs- often stiff extended forelimbs and often a tremor of some type. I have seen in ever Y now and then, but only in dogs that I can recall. They explained it was NOT related to anaesthetic depth, and recommended not to increase the settings or give more propofol. They advised it could be abolished by a micro dose ketamine- roughly 0.1ml for a 20kg dog IV. I have tried this and it does work, though more often the 'reaction' has passed by the time I have got the ketamine ready!

Re: Neurological symptoms in a cat post propofol anaesthesia

mariette asselbergs — Thu, 10 Oct 2013 23:14:49 GMT

Was the ketamine "potentiated" by any chance?

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Mariette

Re: Neurological symptoms in a cat post propofol anaesthesia

John Flynn — Thu, 10 Oct 2013 22:01:01 GMT

[quote user="Michael Woodhouse"]

John - all additional ketamine would achieve is deepening of anaesthesia. It's a continuum that will stop the twitching at some point............

[one of those nuggets of wisdom along with "all bleeding stops eventually..........")

[/quote]

Hehe.

I guess by extension more propofol would have stopped the twitches in Martin's case

Re: Neurological symptoms in a cat post propofol anaesthesia

Michael Woodhouse — Thu, 10 Oct 2013 21:57:55 GMT

John - all additional ketamine would achieve is deepening of anaesthesia. It's a continuum that will stop the twitching at some point............

[one of those nuggets of wisdom along with "all bleeding stops eventually..........")

Re: Neurological symptoms in a cat post propofol anaesthesia

John Flynn — Thu, 10 Oct 2013 21:55:42 GMT

No help at all I'm afraid Martin, but I was once advised by a colelague to give dogs with 'propofol twitches' post-induction 0.5mg/kg ketamine iv.

To this day, I'm still unsure whether there is/was any logic to this or whether this simply gave him/me something to do while the twitches resolved / propofol wore off?

ANyone else party to this folklore?

Re: Neurological symptoms in a cat post propofol anaesthesia

Mark Hedberg — Thu, 10 Oct 2013 19:58:32 GMT

[quote user="Martin Atkinson"]

Another rabies case Mark?

[/quote]

No, but my uncle had to have a bunch of shots because a horse he treated tested positive for rabies. Remember, I've worked in less safe countries so I tend to worry about the little things. I nearly went overboard over my first snakebite case in UK (estimated for hospital, fluids, steroids, guarded prognosis) until someone pointed out that your most toxic snake is the adder, as opposed to the desert sidewinder.

Err on the side of caution? Maybe

Re: Neurological symptoms in a cat post propofol anaesthesia

Martin Atkinson — Thu, 10 Oct 2013 17:26:13 GMT

OK so no takers on this one but worry not. It seems that the cat has always twitched on and off so propofol is off the hook, the owner isn't concerned/hasn't got any money so that's the end of that. Another rabies case Mark?