sublingual buprenorphine

Re: sublingual buprenorphine

Glenn Hodgson — Fri, 22 Feb 2013 09:14:54 GMT

Rabbit skin, touché.

Re: sublingual buprenorphine

James Laidlaw — Fri, 22 Feb 2013 08:42:15 GMT

[quote user="Glenn Hodgson"]

Or did you intend to highlight Matts point?

If so devils advocate> Should I rub honey flavored loxicom/metacam into a dogs skin prior to considering this transdermal gel? http://www.ncbi.nlm.nih.gov/pubmed/21469950

[/quote]

Given Matt's position as a specialist, and how the cascade works I think his point is still valid. Temgesic, not licensed, vetergesic, licensed.

If there was an unlicensed NSAID and a licensed one - you have to use the latter under cascade. So while I recognise your tongue in cheek post, I'm also pedantic enough to point out the shortcomings.

Also, the study was in rabbits, so you should have said rabbits skin, not dogs.

I'm in an odd mood today...

Re: sublingual buprenorphine

Neil Wheadon — Thu, 21 Feb 2013 18:07:05 GMT

[quote user="Glenn Hodgson"]

Were you highlighting the general discussion?>

[/quote]

Yes we've been here before and there some interesting points here, simple as that

Neil

Re: sublingual buprenorphine

Glenn Hodgson — Thu, 21 Feb 2013 17:15:45 GMT

[quote user="Neil Wheadon"]

[quote user="Glenn Hodgson"]look at temgesic tabs[/quote]

See http://www.vetsurgeon.org/forums/p/4141/12158.aspx#12158

Neil

[/quote]

Were you highlighting the general discussion?>

Owner compliance is my own justification for using temgesic over vetergesic/bupcare when I choose to use it.

Or did you intend to highlight Matts point?

If so devils advocate> Should I rub honey flavored loxicom/metacam into a dogs skin prior to considering this transdermal gel? http://www.ncbi.nlm.nih.gov/pubmed/21469950

Re: sublingual buprenorphine

Mark Rowland — Thu, 21 Feb 2013 14:06:46 GMT

[quote user="Neil Wheadon"]

Can I extend this to Rabbits?

[/quote]

Why not...

rabbit saliva is about 9.4 so should be ok as this is fairly similar to cat saliva.

However the effect is variable because of the increased keratinisation of the oral mucosa (because of thier diet). This makes absorption variable at best. (Source D Heard, Zoological prof. University of Florida)

Therefore I dont use this method much.

Hope that helps.

Re: sublingual buprenorphine

Neil Wheadon — Thu, 21 Feb 2013 13:45:11 GMT

[quote user="Glenn Hodgson"]look at temgesic tabs[/quote]

See http://www.vetsurgeon.org/forums/p/4141/12158.aspx#12158

Neil

Re: sublingual buprenorphine

Glenn Hodgson — Thu, 21 Feb 2013 13:41:45 GMT

look at temgesic tabs. Great stuff! dunlops have them in stock.

Re: sublingual buprenorphine

Neil Wheadon — Thu, 21 Feb 2013 13:32:15 GMT

Can I extend this to Rabbits?

I had a client call me Monday night as her rabbit had been prescribed this method and to be honest i knew little about this

Neil

Re: sublingual buprenorphine

Joyce Whitehead — Thu, 21 Feb 2013 13:26:25 GMT

I have also used it post op in a dog with a cervical disc lesion, on the advice of the anaesthetist at the referral practice, as an addition to NSAIDs and the dog was much happier after the administration.

Re: sublingual buprenorphine

a.bardell — Thu, 21 Feb 2013 10:27:21 GMT

I have used oral buprenorphine in dogs post op at same dose as injection and it seemed to work.

Had a dog with autoimmune prob and we had to remove all its nails/nail beds, already on steroid and anyway NSAIDS caused severe GI signs. Dog also got vv stressed when kenneled so used to send home post op with couple of doses of oral buprenorphine for analgesia. Owner a human carer and commented that dog seemed v settled and comfortable with dose.