atopica and vaccinations

Re: atopica and vaccinations

Charlotte Marshall — Thu, 28 Feb 2013 21:12:25 GMT

Have to admit that similarly I am reluctant to mess with stable animals. Usually I will try and get a 48 hr break either side but if they turn up for it without having done that I just tell them to miss the next couple of doses. Animals that are on ongoing steroids are not usually on very high doses, certainly not doses I would use for immunosuppression in cases of IMHA for example, so I doubt it will cause a problem though I do warn them I cannot guarantee full reponse to vaccination.

Re: atopica and vaccinations

Adrienne McPartland — Thu, 28 Feb 2013 20:17:22 GMT

Sorry to hijack this thread, but along similar lines...

How long do other people withdraw steroids for prior to vaccination when dogs are well controlled for conditions such as atopy.

Re: atopica and vaccinations

Rob Loxley — Fri, 15 Feb 2013 23:21:15 GMT

The US datasheet is interestingly more informative on vaccination:

Vaccination effect: The effect of ATOPICA administration on the immunological response to vaccination was evaluated in a study in which 16 dogs were dosed with either ATOPICA at 20 mg/kg/day (4X the initial daily dose) or placebo for 56 days. All dogs were vaccinated on Day 27 with a killed commercial rabies virus and a multivalent vaccine (DHLPP) which included a modified live virus. Antibody titers for rabies, canine distemper, canine adenovirus type 2, parainfluenza, parvovirus, Leptospira canicola, and Leptospira icterohaemmorrhagiae were examined on Days 0, 27 (prior to vaccination), 42 and 56. Quantification of CD4, CD8, and CD3 T-lymphocytes was analyzed. Clinical changes included soft stool and dermatologic changes consistent with those seen in previous studies. Antibody titers did not rise in dogs treated with ATOPICA or the placebo for any component of the multivalent vaccine which included a modified live virus while all animals demonstrated a significant increase in antibody rabies titer by Day 42 or 15 days post-revaccination"

Re: atopica and vaccinations

Mark Holmes — Fri, 15 Feb 2013 16:40:45 GMT

I have just done them. Often I am reluctant to mess with an atopica dog once they are under control. A four week break is potentially more if a worry than vaccine issues. I would feel different in the face of a disease outbreak.

Re: atopica and vaccinations

Nicola Lawlor — Fri, 15 Feb 2013 16:06:43 GMT

I have always followed the 2 weeks either side rule, but I guess you have to take each case individually too. Maybe you could stop only a week before the vaccine and for a week afterwards and see if this is better for the pruritis than a complete 4 weeks?

Re: atopica and vaccinations

Michael Woodhouse — Fri, 15 Feb 2013 13:11:01 GMT

I just crack on with the vaccines despite the Atopica. Warn them it is less than ideal.

It suppresses the immune system, but doesn't obliterate it - or all the dogs would die. We are exposed to pathogens constantly.