https://www.vetsurgeon.org/f/clinical-questions/14327/ferret-with-suspected-insulinoma Had a quick couple of questions regarding an ongoing case. Patient is a 4yo ME ferret presenting with intermittent lethargy. Tentatively diagnosed an insulinoma as deteriorated rapidly in a hospital setting (while closely monitored) when food restricteden-USTelligent Community 10https://www.vetsurgeon.org/thread/83033?ContentTypeID=1Mon, 11 Feb 2013 12:20:48 GMT146601cc-3922-4be7-9974-7e1d4e45a66b:6b681501-9d54-4b0a-b16c-8e4875fafde0Marie Kubiak<p>Insulin is preferable to confirm diagnosis&nbsp;but difficulties lie in preserving samples for testing,&nbsp;samples require sending on ice last time I spoke to&nbsp;our lab about assays. High is diagnostic but even an insulin value in the normal range&nbsp;is considered abnormal as it is inappropriate for a hypoglycaemic state. On preds the values may not be reliable though. I would be highly suspicious of an insulinoma from repeated low measurements (3.4mmol/l is usually used as the cut off value).</p> <p>I prefer to use diazoxide for control where possible - more expensive than preds but it is a more specific therapy. Surgery is an option but many insulinomas are microadenomas so accurate localisation for removal can be impossible.</p> <p>Marie</p><div style="clear:both;"></div>