Re: Rabbit Osteosarcoma

Richard Saunders — Fri, 01 Feb 2013 14:26:54 GMT

there is a small amount online. I enclose a copy of the first page of results, and the abstract of one paper. LAPIS and WILDPRO would be good things to look on (there is a LAPIS citation here).

In general terms, the first things I would want to know are the age of rabbit, the health of the rabbit, the site, and whether there is definitive histopathological diagnosis, before being more specific.

Hope this is of some use:

Richard

Osteosarcoma with multiple metastases and subcutaneous ...

www.ncbi.nlm.nih.gov/pubmed/15195269

Osteosarcoma with multiple metastases and subcutaneous involvement in a rabbit (Oryctolagus cuniculus). Mazzullo G, Russo M, Niutta PP, De Vico G.

Full Article - Wiley Online Library

onlinelibrary.wiley.com/doi/10.1111/j.1939-165X.2004.tb00356.x/full

5 Mar 2008 ... Objective: The purpose of this study was to describe the clinical and pathologic findings in a rabbitwith osteosarcoma and multiple metastases ...

Spontaneous Osteosarcoma in a Rabbit (Oryctolagus cuniculus)

intl-vet.sagepub.com/content/44/5/691.full

This case was diagnosed as osteosarcoma by clinical, radiographic, and histologic findings. This is a rare case report of osteosarcoma in a rabbit consistent with ...

Extraskeletal fibroblastic osteosarcoma in a rabbit - Vetstream

www.vetstream.com/lapis/Content/Freeform/fre20009 - Cached

Abstract: Extraskeletal fibroblastic osteosarcoma in a rabbit (Oryctolagus cuniculus) information from Vetstream Lapis.

Osteoblastic Osteosarcoma in a Rabbit - Europe PMC Article ...

europepmc.org/articles/PMC3318249/

An osteosarcoma developed in the tarsal joint region involving the distal tibia of a domestic rabbit (Oryctolagus cuniculus). Micrometastases were present in the ...

Spinal osteolytic osteosarcoma in a pet rabbit -- Weiss and Müller ...

veterinaryrecord.bmj.com/content/168/10/266.2.extract

OSTEOLYTIC osteosarcoma has not been reported previously in rabbits. This short communication describes a case of a pet rabbit with osteolytic osteosarcoma ...

BunSpace.com Forum: Osteosarcoma in Rabbits

www.bunspace.com/forum/thread?tid=16009&posts_tgp_no... - Cached

Forums Thread titled Osteosarcoma in Rabbits at Bunspace.com.

Osteoblastic Osteosarcoma in a Rabbit

www.ingentaconnect.com/content/aalas/cm/2012/00000062/.../art00006

1 Apr 2012 ... An osteosarcoma developed in the tarsal joint region involving the distal tibia of a domestic rabbit(Oryctolagus cuniculus). Micrometastases ...

Vet Clin Pathol. 2004;33(2):102-4.

Osteosarcoma with multiple metastases and subcutaneous involvement in a rabbit (Oryctolagus cuniculus).

Mazzullo G, Russo M, Niutta PP, De Vico G.

Source

Department of Veterinary Public Health, Unit of Pathology, Faculty of Veterinary Medicine, University of Messina, Messina, Italy. gmazzull@unime.it

Abstract

BACKGROUND:

Osteogenic sarcomas are rare in rabbits, but cases involving the mandible, ribs, frontal bones, and tibia have been reported.

OBJECTIVE:

The purpose of this study was to describe the clinical and pathologic findings in a rabbit with osteosarcoma and multiple metastases with subcutaneous involvement.

METHODS:

A 1-year-old female Polish rabbit was evaluated for dysorexia, lameness, gait difficulties with the hind limbs, and the presence of 2 subcutaneous nodules, on the left thigh and in the dorsal region. A hard swelling was also present at the base of the tail. Radiographic findings revealed multiple abnormalities in several bones, which were more severe in the sacrococcygeal region and femur. Several areas of calcification involving the thorax and abdomen as well as skeletal muscles, also were noted. The thigh nodule was surgically removed, and cytologic and histologic evaluations were performed. Following the rabbit's death, postmortem radiographs were taken and necropsy was performed. Samples of tissues and organs, involved bone segments, and other subcutaneous nodules were collected and examined by cytology and histology.

RESULTS:

Both the subcutaneous nodules and the majority of tissues and organs contained neoplastic cells whose appearance was consistent with osteogenic sarcoma.

CONCLUSION:

Clinical, radiologic, and pathologic data supported a diagnosis of osteosarcoma with multiple metastases and subcutaneous involvement.