Chronic Rhinitis in dog

Re: Chronic Rhinitis in dog

Rob Loxley — Wed, 19 Sep 2012 00:19:50 GMT

[quote user="Andrew Mellor"] the best I seem to be able to get is a snotty dog[/quote]

sometimes that's the best you can get
I had a case that went to a number of referral centres and had every test and treatment, even had a unilateral turbinectomy, but remained snotty forever

I have heard of people using itraconazole longterm in LP rhinitis cases (that don't have primary fungal rhinitis), though I forget the exact rationale

by the by, what is the sensitivity and specificity of aspergillus serology for diagnosis of fungal rhinitis; the cases I've seen have been diagnosed by rhinoscopy and cytology of plaques?

Re: Chronic Rhinitis in dog

Nicola Lawlor — Tue, 18 Sep 2012 22:13:35 GMT

What does the visible nose look like - is it red raw under the nostrils? If so then there is a very high chance this is aspergillus. I had a similar case in a rottie a few years back and everything came back negative. After much discussion with various specialists we went ahead without a confirmation and drilled into the frontal sinuses on each side and packed full of Canestan cream. Much improvement on round one, repeated a further two times some weeks later as discharge gradually increasing and the dog was then well in remission after this. Apparently there is a significantly high % will cure on the first treatment.

Re: Chronic Rhinitis in dog

Evelyn Barbour-Hill — Tue, 18 Sep 2012 17:23:52 GMT

Hmmm. Dunno. Does any antibiotic stand out as being particularly effective?

Possibly you could trephine the frontal sinuses and use them as depot sites to trickle medication, by filling them with a topical gel or cream? With the owner's full understanding, of course.

I did once solve what seemed to be an intractable problem by introducing Otomax via the sinus. I'm not suggesting that would necessarily be a good thing to do (and the case was rather different, the problem having arisen originally from damage by a foreign body) but it can be done.

And, er, teaching granny to suck eggs I know, but nasal biopsies can be misleading.

PS. What breed is it?

Re: Chronic Rhinitis in dog

Andrew Mellor — Tue, 18 Sep 2012 15:48:46 GMT

sedate and flushed nose repeatedly last week and he had 2 days with zero discharge we were all really hopeful but it did not last back to the clear slightly grey mucous everywhere !!!!

Re: Chronic Rhinitis in dog

Andrew Mellor — Tue, 18 Sep 2012 15:46:32 GMT

[quote user="Evelyn Barbour-Hill"]

What were the findings?

[/quote]

radiography normal on all views, endoscopy - red swollen mucosa biopsy just inflammatory reaction, +++ thick mucous in nasopharynx , serology negative for aspergillosis , culturesall been negative fungal and bacterial.

Re: Chronic Rhinitis in dog

Evelyn Barbour-Hill — Tue, 18 Sep 2012 14:00:52 GMT

[quote user="Andrew Mellor"]yes to all these[/quote]

What were the findings?

Sinus trephining is easy and dogs tolerate bits of rubber tube stuck out of their foreheads very well. The flushing would be really unpleasant though – I presume you'd be doing it fully conscious if it was done daily. It could work.

Re: Chronic Rhinitis in dog

Hannah Wynne Richards — Tue, 18 Sep 2012 13:59:23 GMT

It could be fungal of some sort although aspergillus neg,so I suppose that's an added reason for trying ketoconazole before heroic surgery

Good luck

Wynne

Re: Chronic Rhinitis in dog

Andrew Mellor — Tue, 18 Sep 2012 13:52:31 GMT

[quote user="Evelyn Barbour-Hill"]

Have you done:

radiography

endoscopy in every direction

aspergillus serology

[/quote]

yes to all these , and also to immunocomprimising doses of steroids, various ab's have been used whenever the discharge has become green or purulent looking but even then nothing has been cultured.

does anyone thing ketoconazole could help as it has some immunomodulating effects doesn't it or maybe atopica ?

I have tried inhalled steroid as well but this seemed to have no effect, neither did combinations of antihistamine.

Re: Chronic Rhinitis in dog

Evelyn Barbour-Hill — Mon, 17 Sep 2012 17:51:06 GMT

Have you done:

radiography

endoscopy in every direction

aspergillus serology

Re: Chronic Rhinitis in dog

Martin Atkinson — Mon, 17 Sep 2012 16:58:50 GMT

Bisolvon? Maybe immune mediated, could try some corticsteroids but make sure its not Aspergillus first. Sinus trefining sounds worse than the problem. We have a minature Dachshund with this problem, its been to the RVC and had every test under the sun and eliminated aspergillus as far as possible, trefining was not mentioned as a possibility. Bisolvon and antibiotics (Ronaxan) was the only thing to give it some relief, maybe the doxocyclin has some immunomodulatory effect.