Asthma

Re: Asthma

Kate Richardson — Fri, 27 Jul 2012 15:27:44 GMT

I guess another possibility would be reduced GIT absorption, especially in an older cat. I have heard of IBD cases where injectable corticosteroids work but oral don't for this reason.

Re: Asthma

Elizabeth Tuley — Fri, 27 Jul 2012 08:28:53 GMT

I have a similar situation. 17yr old DSH with suspected feline asthma, responds really well to injectable dex but deteriorates as soon as move onto oral steroids. This cat used to be a medically managed hyperthyroid (bilateral thyroidectomy about 6 months ago) and the owner is insistent that the tablets are getting down.

Re: Asthma

Christopher Saul — Thu, 26 Jul 2012 23:59:18 GMT

[quote user="James Laidlaw"]wondering if there's any difference in action between oral pred and injectable dexafort?)[/quote]

Potency is one difference; dexamethosone is about 7-8 times the glucocorticoid activity of prednisolone. That said, I agree owner compliance is prob the main issue. You could certainly consider inhaled glucocorticoids too as Martin says

Secondary respiratory infections may also confound clincial response of course.

Chris

Re: Asthma

Martin Atkinson — Thu, 26 Jul 2012 18:22:54 GMT

[quote user="Michael Woodhouse"]

Or (dare I say it) Depomedrone!

[/quote]

Re: Asthma

Michael Woodhouse — Thu, 26 Jul 2012 17:27:55 GMT

Or (dare I say it) Depomedrone!

Re: Asthma

Mark Holmes — Thu, 26 Jul 2012 14:42:41 GMT

Try generic soluable pred, I have never had a cat refuse to take them...ever!

Re: Asthma

James Laidlaw — Wed, 25 Jul 2012 13:12:07 GMT

Thanks Martin. Just a really nice client and indoor cat - asked him to check for any spat out tablets and we'll try crushing into food until aerokat arrives and see if any change. Just wondering if there's any difference between the pharmacology of the long acting dexafort injection and pred tablets...

Re: Asthma

Martin Atkinson — Wed, 25 Jul 2012 12:40:35 GMT

So long as you've got your diagnosis right, I think you hit the nail on the head - lack of client compliance. I nearly always start my asthmatics on a dose of dexamethasone then initially maintain with preds but will try and get them all on inhaled medication with an Aerokat and fluticasone or beclamethasone.