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<?xml-stylesheet type="text/xsl" href="https://www.vetsurgeon.org/utility/feedstylesheets/rss.xsl" media="screen"?><rss version="2.0" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:slash="http://purl.org/rss/1.0/modules/slash/" xmlns:wfw="http://wellformedweb.org/CommentAPI/"><channel><title>Cyclophosphamide</title><link>https://www.vetsurgeon.org/f/clinical-questions/12220/cyclophosphamide</link><description> I have just had a discussion with an oncologist about post-surgical options for a dog with an incompletely excised soft tissue sarcoma. One option which has been suggested is cyclophosphamide and metacam daily until signs of recurrence of the tumour</description><dc:language>en-US</dc:language><generator>Telligent Community 10</generator><item><title>Re: Cyclophosphamide</title><link>https://www.vetsurgeon.org/thread/68297?ContentTypeID=1</link><pubDate>Thu, 19 Jul 2012 13:31:36 GMT</pubDate><guid isPermaLink="false">146601cc-3922-4be7-9974-7e1d4e45a66b:0ac2ed71-97e4-4d32-8c13-cc2a445a412c</guid><dc:creator>Martin Atkinson</dc:creator><description>&lt;p&gt;[quote user=&amp;quot;Rob Davis&amp;quot;]Most people on chemotherapy don&amp;#39;t pee and poo in the garden or out in public, nor do they slobber on other people (or at least only those they know really well....)[/quote] Peeing and pooing in the garden would be&amp;nbsp;infinitely&amp;nbsp;preferable to what they do which is peeing and pooing into the public sewers which is then recycled for human consumption, and hopefully they would choose not to kiss their nearest and dearest. There are clear guidelines for dealing with body fluids in clinic which can be adapted to home use. I tell all my clients with chemo patients that there is a risk, I do not assume it is insignificant but the point I was making was that it has to be put into context. Half of them will be smoking, drinking alcohol and eating processed meats or indulging in other life-style habits all of which are far more carcinogenic than the very small quantity of cyclosphosphamide that may be excreted from their pets and which they are not&amp;nbsp;likely&amp;nbsp;to come in contact with unless they are careless.&lt;/p&gt;&lt;div style="clear:both;"&gt;&lt;/div&gt;</description></item><item><title>Re: Cyclophosphamide</title><link>https://www.vetsurgeon.org/thread/68292?ContentTypeID=1</link><pubDate>Thu, 19 Jul 2012 12:43:03 GMT</pubDate><guid isPermaLink="false">146601cc-3922-4be7-9974-7e1d4e45a66b:6ccbed29-27d9-466c-bc7b-e56f00b9ad39</guid><dc:creator>Rob Davis</dc:creator><description>&lt;p&gt;[quote user=&amp;quot;Martin Atkinson&amp;quot;]Come to think of it neither would the medics![/quote]&lt;/p&gt;
&lt;p&gt;Most people on chemotherapy don&amp;#39;t pee and poo in the garden or out in public, nor do they slobber on other people (or at least only those they know really well....)&lt;/p&gt;
&lt;p&gt;[quote user=&amp;quot;Martin Atkinson&amp;quot;]Whatever happened to common sense?[/quote]&lt;/p&gt;
&lt;p&gt;I&amp;#39;m quite happy to apply common sense, but I have no idea what quantities are likely to be excreted or how much of a risk this is. Assuming there is no significant risk seems a little gung&amp;#39;ho to me.&lt;/p&gt;&lt;div style="clear:both;"&gt;&lt;/div&gt;</description></item><item><title>Re: Cyclophosphamide</title><link>https://www.vetsurgeon.org/thread/68244?ContentTypeID=1</link><pubDate>Wed, 18 Jul 2012 18:18:26 GMT</pubDate><guid isPermaLink="false">146601cc-3922-4be7-9974-7e1d4e45a66b:a5bf2eb0-8d7d-4ce1-bc3a-90d44ab37890</guid><dc:creator>Martin Atkinson</dc:creator><description>&lt;p&gt;I think sensible precautions are.... well sensible but if you worry about chemotherapeutic agents getting into the environment or&amp;nbsp;contaminating&amp;nbsp;the owner then we wouldn&amp;#39;t do any chemotherapy at all. Come to think of it neither would the medics! Whatever happened to common sense?&lt;/p&gt;&lt;div style="clear:both;"&gt;&lt;/div&gt;</description></item><item><title>Re: Cyclophosphamide</title><link>https://www.vetsurgeon.org/thread/68184?ContentTypeID=1</link><pubDate>Wed, 18 Jul 2012 13:45:37 GMT</pubDate><guid isPermaLink="false">146601cc-3922-4be7-9974-7e1d4e45a66b:c01fa8e0-97d0-4478-aaed-8ac39af9cbe5</guid><dc:creator>Rob Loxley</dc:creator><description>&lt;p&gt;I&amp;#39;d suggest your friendly oncologist may give a better answer, but my understanding was that with the lower doses of chemo agents used for such &amp;#39;metronomic&amp;#39; protocols the risk was less, but the same sensible precautions should be taken to minimise exposure as, say, a dog on COP.&lt;/p&gt;
&lt;p&gt; I&amp;#39;d be interested to know how long hazardous metabolites stay in the enviroment &amp;nbsp;(e.g. dog urinating on the lawn), but I&amp;#39;m not sure I&amp;#39;d be massively more concerned than, say, COP.&lt;/p&gt;&lt;div style="clear:both;"&gt;&lt;/div&gt;</description></item></channel></rss>