Longterm omeprazole in vomiting dog

Re: Longterm omeprazole in vomiting dog

Christopher Saul — Sat, 02 Jun 2012 22:02:41 GMT

The same theoretical risks of long term omeprazole are applied to humans, though my Father's been on it for about 3 years now and the doctors don't seem to worry...

Re: Longterm omeprazole in vomiting dog

David Mills — Sat, 02 Jun 2012 16:10:38 GMT

Omeprazole has never been shown to cause rural hypertrophy in the clinical setting, either in animals or humans.

I think you do have a diagnosis - LPG/E - but the prednisolone doses are far too low - you need immunosuppressive doses for this not anti-inflammatory. Also consider corticosteroid injections (daily dexameth) as bowel oedema/inflammation can prevent full absorption of the medication.

Re: Longterm omeprazole in vomiting dog

Mark Hedberg — Fri, 01 Jun 2012 15:04:02 GMT

I've heard of the occasional resistant helicobacter; when I was treated for it, I was on ranitidine+amox/clav+clarithromycin, as opposed to metronidazole.

According to the BSAVA Small animal Formulary, 7th ed: "Chronic suppression of acid secretion has caused hypergastrinaemia in laboratory animals, leading to mucosal cell hyperplasia, rugal hypertrophy and the development of carcinoids, so treatment for max of 8 weeks has been recommended. However, such problems have not been reported in companion animals. Adverse effects do include nausea, diarhhoea, constipation and skin rashes."

edit: how's the worming history?