Trocoxil

Re: Trocoxil

Jacquin Mitchell — Tue, 20 Mar 2012 17:53:09 GMT

I used Trocoxil on my old boy who has neurological damage LH and Arthritis RH. For pain relief it was fab, but he started losing weight and when we looked at his bloods , his liver enzymes and bile acids were up. I'm pretty sure this was a concurrent problem but trocoxil didn't help. He's a few months off it now, and on tramadol. His blood levels are still raised but much better than before but he's a lot less mobile.

Re: Trocoxil

Martin Atkinson — Tue, 20 Mar 2012 17:23:20 GMT

I have one experience of using Trocoxil in a dog which had tolerated both meloxicam and carprophen well previously, It suffered a life threatening bout of HGE within a few days of starting it.. Pfizer assured me that a) the GI side effects would have started after 24-48 hrs if it was the Trocoxil and b) that treatment would be just as effective as in another dog on a daily dose on one of the other NSAIDs which had had the medication withdrawn at the onset of illness i.e. a long acting NSAID is no more likely to compromise treatment due its side effects than a short acting one. I'm not convinced. I will not be using it again in a hurry.

Re: Trocoxil

Colin Thomson — Tue, 20 Mar 2012 07:49:54 GMT

[quote user="Michael Woodhouse"]

[quote user="Colin Thomson"] For him, its at least as good as metacam, rimadyl, previcox or clindacyl.[/quote]

I never knew it had anti-bacterial properties............

[/quote]

Well I don't know the names of them all..... Cimalgex - there, is that better?

If my partner would just stop being persuaded by reps to try all these new drugs. She's a sucker for a good sales pitch.

Colin

Re: Trocoxil

Michael Woodhouse — Mon, 19 Mar 2012 23:14:16 GMT

[quote user="Colin Thomson"] For him, its at least as good as metacam, rimadyl, previcox or clindacyl.[/quote]

I never knew it had anti-bacterial properties............

Re: Trocoxil

Luciano Nebiante PGCertSAS — Mon, 19 Mar 2012 22:04:53 GMT

Thanks for all your replies, very helpful.

I might give it a go, and see how my patients respond.

Re: Trocoxil

John Rimmer — Sat, 17 Mar 2012 11:28:47 GMT

Yes but using it in the month off helps sales of Rimadyl :)

Re: Trocoxil

Thomas Johnson — Sat, 17 Mar 2012 09:48:10 GMT

[quote user="robloxley"]

I chuckled when the rep advised for pain relief during the 'month off' to put the dog back on Rimadyl.

[/quote]

I thought there was supposed to be no need for additional pain relief in the month off due to build up of the Trocoxil in the dog's system? Also the European license doesn't include having a month off...

Re: Trocoxil

Rob Loxley — Fri, 16 Mar 2012 23:37:41 GMT

[quote user="Kate Richardson"]have used 'newer safer better' NSAIDs such as Cimalgex and Onsior and have to say Rimadyl and Metacam still get my vote in terms of pain relief and effectiveness[/quote]

Most of the 'newer safer better' claim only to be equally effective as Rimadyl and only equally 'safe'. For the 95% of dogs that happily munch the Rimadyl, give them Rimadyl? I chuckled when the rep advised for pain relief during the 'month off' to put the dog back on Rimadyl.

Re: Trocoxil

Rob Loxley — Fri, 16 Mar 2012 23:37:41 GMT

[quote user="Kate Richardson"]have used 'newer safer better' NSAIDs such as Cimalgex and Onsior and have to say Rimadyl and Metacam still get my vote in terms of pain relief and effectiveness[/quote]

Re: Trocoxil

Colin Thomson — Fri, 16 Mar 2012 22:35:05 GMT

My own dog is on Trocoxil. For him, its at least as good as metacam, rimadyl, previcox or clindacyl. And his owner doesn't have to remember to make sure he has his tablet every night. He's been on it for over a year - it easily lasts a month.

Colin

Re: Trocoxil

Joyce Whitehead — Fri, 16 Mar 2012 22:31:45 GMT

I've had mixed responses - much like other NSAIDs .

But for some of the dogs we have on it, they have been transformed by it, especially one dog with chronic hock arthritis who was really unwilling to exercise on either rimadyl or metacam, but is happy and moving well on trocoxil. I think it is like all of the nsaids, some dogs seem to do better on one than the other.

It certainly took me quite a while to try it as it seemed odd to give a drug that was in the system so long, but I do feel it has a place, not as frontline treatment maybe, but in the chronic cases can be useful. We have one dog who lives with his disabled owner in care (a Leonard Cheshire home), and the staff and owner would not cope easily with daily meds, but once a month is so much easier to manage - one member of staff is in charge of his meds and dosing him.

Re: Trocoxil

Kate Richardson — Fri, 16 Mar 2012 22:27:34 GMT

I haven't used Troxocil and haven't been tempted so can't comment, but have used 'newer safer better' NSAIDs such as Cimalgex and Onsior and have to say Rimadyl and Metacam still get my vote in terms of pain relief and effectiveness with minimal side effects in most dogs. Dogs that don't get on with nsaids don't get on with nsaids generally. Always get exceptions, but still a metacam/rimadyl fan

Re: Trocoxil

Ian Mostyn — Fri, 16 Mar 2012 21:50:06 GMT

The first three cases I used it on all came back and asked for Rimadyl again. I wasn't impressed with Previcox either. Haven't tried it for over a year now and no great urge to go back.

Ian

Re: Trocoxil

Julie Innes — Fri, 16 Mar 2012 21:17:07 GMT

Hate to be the sole voice of negativity but I tried it on my old boy, who was doing ok on meloxicam. I could hardly wait until the 2wks were up as he was so sore and stiff, and went back to the meloxicam without giving the second dose.

Also tried it on another long-term arthritis case, and he really didn't do well on it either! I realise 2 cases don't mean much, but it has made me somewhat reluctant to keep trying it! I had such high hopes for it too..

Re: Trocoxil

Luciano Nebiante PGCertSAS — Fri, 16 Mar 2012 20:46:37 GMT

Well, everyone seems to have good experience with it, and Bob's Staffie looks forward to it!

But any not positive experience or a poorer response than expected?

Re: Trocoxil

John Rimmer — Fri, 16 Mar 2012 17:55:33 GMT

Presumably because they might need glucocorticoids in the future?

Re: Trocoxil

Sarah Keir — Fri, 16 Mar 2012 17:47:32 GMT

I just can't get the name 'Toxocil' out of my head

Re: Trocoxil

Rob Loxley — Fri, 16 Mar 2012 17:30:50 GMT

[quote user="Julian Earl"]avoid dogs with a history of atopy[/quote]

Re: Trocoxil

Bob Russell — Fri, 16 Mar 2012 15:59:41 GMT

Just about to start my Staffie on it. If she goes back to her old self and runs away again I will not be giving her the second dose in two weeks. She can limp!

Re: Trocoxil

Evelyn Barbour-Hill — Fri, 16 Mar 2012 15:56:58 GMT

It's good.

Re: Trocoxil

Julian Earl — Fri, 16 Mar 2012 15:43:36 GMT

Excellent treatment for long-term arthritis cases (i.e. most!). I'm a big fan.

We use it a lot and have had people whose dog has been on other NSAIDs say how much better the pet has been on Trocoxil. I believe that the marketing from Pfizer about the 24 hours-per-day relief is accurate, based on the dogs activity and owners' perceptions. The owners like the convenience, and they like the little fridge magnet as a reminder to dose as well.

We have suffered no significant number of side-effects, maybe the odd diarrhoea but no more than you get with say meloxicam. You do need to pick your cases and avoid dogs with a history of atopy, but on the other hand I've anaesthetised Trocoxil dogs without problem. A long-term NSAID does seem counter-intuitive, but any worries have been unfounded so far.

As I said, yep, I'm a fan.